NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with pancreatic cancer. [provided by RefSeq, Jul 2008]
Uniprot Description
HOXB2: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Antp homeobox family. Proboscipedia subfamily.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 17q21.32
Cellular Component: cytosol; nuclear speck; nucleoplasm; nucleus
Molecular Function: sequence-specific DNA binding
Biological Process: anterior/posterior pattern specification; blood circulation; dorsal/ventral pattern formation; embryonic skeletal morphogenesis; facial nerve structural organization; morphogenesis of an epithelial sheet; multicellular organism development; neural nucleus development; positive regulation of transcription from RNA polymerase II promoter; rhombomere 3 development; rhombomere 4 development; transcription from RNA polymerase II promoter
Research Articles on HOXB2
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Product Notes
The Human, Mouse HOXB2 hoxb2 (Catalog #AAA9502194) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9502194 ELISA Kit recognizes Human, Mouse HOXB2. It is sometimes possible for the material contained within the vial of "HOXB2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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