KCC4 / SLC12A7 Blocking Peptide | SLC12A7 blocking peptide
KCC4 / SLC12A7 Immunizing Peptide
NCBI and Uniprot Product Information
Uniprot Description
KCC4: Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification. Belongs to the SLC12A transporter family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Transporter; Membrane protein, multi-pass; Transporter, SLC family
Chromosomal Location of Human Ortholog: 5p15
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: potassium ion symporter activity; potassium:chloride symporter activity; protein kinase binding
Biological Process: cell volume homeostasis; ion transport; synaptic transmission; transport
Research Articles on SLC12A7
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Product Notes
The SLC12A7 slc12a7 (Catalog #AAA425174) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The KCC4 / SLC12A7 Immunizing Peptide reacts with Human, Mouse and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: C-QLIHDRNT ASHT. It is sometimes possible for the material contained within the vial of "KCC4 / SLC12A7, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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