anti-Human, Mouse RREB1 Antibody | anti-RREB1 antibody

RREB1 Antibody

Cat. Num. AAA852132

• Gene Names: RREB1; HNT; FINB; LZ321; Zep-1; RREB-1
• Reactivity: Human, Mouse
• Applications: Immunohistochemistry, ELISA
• Purity: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: RREB1; RREB1 Antibody; RREB-1; Raf-responsive zinc finger protein LZ321; Zinc finger motif-enhancer binding-protein 1; Zep-1; Finger protein in nuclear bodies; Ras-responsive element-binding protein 1; zinc-finger motif-enhancer binding-protein-1; anti-RREB1 antibody

• Reactivity: Human, Mouse
• Specificity: RREB1 antibody detects endogenous levels of total RREB1 protein.
• Purity/Purification: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Sequence Length: 1687

• Applicable Applications for anti-RREB1 antibody: Immunohistochemistry (IHC), ELISA (EIA)
• Application Notes: IHC: 1:50-1:100; ELISA: 1:20000
• Immunogen: The antiserum was produced against synthesized peptide derived from internal of human RREB1.
• Preparation and Storage: Store at-20 degree C for 1 year.

Immunohistochemistry (IHC)

(Peptide-+ Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using RREB1 antibody.)

Product Categories/Family for anti-RREB1 antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells

References

Fujimoto-Nishiyama A., Gene 195:267-275(1997). Date S., Int. J. Mol. Med. 13:637-642(2004). The MGC Project Team; Genome Res. 14:2121-2127(2004).

NCBI and Uniprot Product Information

• NCBI GI #: 51173735
• NCBI GeneID: 6239
• NCBI Accession #: NP_001003698.1
• NCBI GenBank Nucleotide #: NM_001003698.3
• UniProt Accession #: Q92766; O75567; O75568; Q5VYB2; Q6BEP5; Q6BEP6; Q6BEP8; Q86SU2; Q9Y474; A2RRF5; E2GM80; E2GM81
• Molecular Weight: 34,614 Da
• NCBI Official Full Name: ras-responsive element-binding protein 1 isoform 2
• NCBI Official Synonym Full Names: ras responsive element binding protein 1
• NCBI Official Symbol: RREB1
• NCBI Official Synonym Symbols: HNT; FINB; LZ321; Zep-1; RREB-1
• NCBI Protein Information: ras-responsive element-binding protein 1
• UniProt Protein Name: Ras-responsive element-binding protein 1
• Protein Family: Ras-responsive element-binding protein
• UniProt Gene Name: RREB1
• UniProt Synonym Gene Names: FINB; RREB-1; Zep-1

NCBI Description

The protein encoded by this gene is a zinc finger transcription factor that binds to RAS-responsive elements (RREs) of gene promoters. It has been shown that the calcitonin gene promoter contains an RRE and that the encoded protein binds there and increases expression of calcitonin, which may be involved in Ras/Raf-mediated cell differentiation. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

Uniprot Description

Transcription factor that binds specifically to the RAS-responsive elements (RRE) of gene promoters. May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression. Represses the angiotensinogen gene. Negatively regulates the transcriptional activity of AR. Potentiates the transcriptional activity of NEUROD1.