Immunohistochemistry (IHC)
(Peptide-+ Immunohistochemistry analysis of paraffin-embedded human cervix carcinoma tissue using POLG2 antibody.)
anti-Human, Mouse POLG2 Antibody | anti-POLG2 antibody
POLG2 Antibody
Gene Names
POLG2; HP55; POLB; PEOA4; POLGB; MTPOLB; POLG-BETA
Reactivity
Human, Mouse
Applications
Immunohistochemistry, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
POLG2; POLG2 Antibody; DNA polymerase subunit gamma-2; mitochondrial; EC 2.7.7.7; Mitochondrial DNA polymerase accessory subunit; PolG-beta; MtPolB; DNA polymerase gamma accessory 55 kDa subunit; p55; anti-POLG2 antibody
Reactivity
Human, Mouse
Specificity
POLG2 antibody detects endogenous levels of total POLG2 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
485
Applicable Applications for anti-POLG2 antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:50-1:100
ELISA: 1:20000
ELISA: 1:20000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human POLG2.
Preparation and Storage
Store at-20 degree C for 1 year.
Immunohistochemistry (IHC)
(Peptide-+ Immunohistochemistry analysis of paraffin-embedded human cervix carcinoma tissue using POLG2 antibody.)
Immunohistochemistry (IHC)
(Peptide-+ Immunohistochemistry analysis of paraffin-embedded human cervix carcinoma tissue using POLG2 antibody.)
Product Categories/Family for anti-POLG2 antibody
References
Lim S.E., J. Biol. Chem. 274:38197-38203(1999). Johnson A.A., Biochemistry 39:1702-1708(2000).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
54,911 Da
NCBI Official Full Name
DNA polymerase subunit gamma-2, mitochondrial
NCBI Official Synonym Full Names
DNA polymerase gamma 2, accessory subunit
NCBI Official Symbol
POLG2
NCBI Official Synonym Symbols
HP55; POLB; PEOA4; POLGB; MTPOLB; POLG-BETA
NCBI Protein Information
DNA polymerase subunit gamma-2, mitochondrial
UniProt Protein Name
DNA polymerase subunit gamma-2, mitochondrial
Protein Family
UniProt Gene Name
POLG2
UniProt Synonym Gene Names
MTPOLB; p55
NCBI Description
This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.[provided by RefSeq, Sep 2009]
Uniprot Description
Mitochondrial polymerase processivity subunit. Stimulates the polymerase and exonuclease activities, and increases the processivity of the enzyme. Binds to ss-DNA.
Research Articles on POLG2
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Product Notes
The POLG2 polg2 (Catalog #AAA856064) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The POLG2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's POLG2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:50-1:100 ELISA: 1:20000. Researchers should empirically determine the suitability of the POLG2 polg2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "POLG2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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