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Testing Data

anti-Human, Mouse LTBR Antibody | anti-LTBR antibody

LTBR Antibody

Gene Names
LTBR; TNFCR; TNFR3; D12S370; TNFR-RP; TNFRSF3; TNFR2-RP; LT-BETA-R; TNF-R-III
Reactivity
Human, Mouse
Applications
Western Blot, Immunofluorescence, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
LTBR; LTBR Antibody; Tumor necrosis factor receptor superfamily member 3 [Precursor]; Lymphotoxin-beta receptor; Tumor necrosis factor receptor 2-related protein; Tumor necrosis factor C receptor; D12S370; TNFCR; TNFRSF3; anti-LTBR antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse
Specificity
LTBR antibody detects endogenous levels of total LTBR protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
416
Applicable Applications for anti-LTBR antibody
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:40000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human LTBR.
Preparation and Storage
Store at-20 degree C for 1 year.

Testing Data

Testing Data

Western Blot (WB)

(Peptide-+ Western blot analysis of extracts from HeLa cells and HepG2 cells, using LTBR antibody. Immunofluorescence analysis of HeLa cells, using LTBR antibody.)

Western Blot (WB) (Peptide-+ Western blot analysis of extracts from HeLa cells and HepG2 cells, using LTBR antibody. Immunofluorescence analysis of HeLa cells, using LTBR antibody.)
References
Baens M., Genomics 16:214-218(1993). Crowe P.D., Science 264:707-710(1994). Wu M.-Y., J. Biol. Chem. 274:11868-11873(1999).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
44,810 Da
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 3 isoform 2
NCBI Official Synonym Full Names
lymphotoxin beta receptor
NCBI Official Symbol
LTBR
NCBI Official Synonym Symbols
TNFCR; TNFR3; D12S370; TNFR-RP; TNFRSF3; TNFR2-RP; LT-BETA-R; TNF-R-III
NCBI Protein Information
tumor necrosis factor receptor superfamily member 3
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 3
UniProt Gene Name
LTBR
UniProt Synonym Gene Names
D12S370; TNFCR; TNFR3; TNFRSF3; TNF-RIII; TNFR-III

NCBI Description

This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Aug 2012]

Uniprot Description

Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs.

Research Articles on LTBR

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Product Notes

The LTBR ltbr (Catalog #AAA8509742) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The LTBR Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's LTBR can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF), ELISA (EIA). WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:40000. Researchers should empirically determine the suitability of the LTBR ltbr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LTBR, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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