anti-Human, Mouse DDX3Y Antibody | anti-DDX3Y antibody

DDX3Y Antibody

Cat. Num. AAA852585

• Gene Names: DDX3Y; DBY
• Reactivity: Human, Mouse
• Applications: Immunohistochemistry, ELISA
• Purity: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: DDX3Y; DDX3Y Antibody; ATP-dependent RNA helicase DDX3Y; DBY; DDXY; DEAD (Aspartate-glutamate-alanine-aspartate) box polypeptide; Y chromosome; DEAD-box protein 3; Y-chromosomal; EC 3.6.1.-; anti-DDX3Y antibody

• Reactivity: Human, Mouse
• Specificity: DDX3Y antibody detects endogenous levels of total DDX3Y protein.
• Purity/Purification: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Sequence Length: 660

• Applicable Applications for anti-DDX3Y antibody: Immunohistochemistry (IHC), ELISA (EIA)
• Application Notes: IHC: 1:50-1:100; ELISA: 1:20000
• Immunogen: The antiserum was produced against synthesized peptide derived from internal of human DDX3Y.
• Preparation and Storage: Store at-20 degree C for 1 year.

Immunohistochemistry (IHC)

(Peptide-+ Immunohistochemistry analysis of paraffin-embedded human brain tissue using DDX3Y antibody.)

Product Categories/Family for anti-DDX3Y antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells

References

Brill L.M., Anal. Chem. 76:2763-2772(2004). Sekiguchi T., Exp. Cell Res. 300:213-222(2004). Rush J., Nat. Biotechnol. 23:94-101(2005).

NCBI and Uniprot Product Information

• NCBI GI #: 169881239
• NCBI GeneID: 8653
• NCBI Accession #: NP_001116137.1
• NCBI GenBank Nucleotide #: NM_001122665.3
• UniProt Accession #: O15523; Q8IYV7; B4DK29; B4DXX7
• Molecular Weight: 32,416 Da
• NCBI Official Full Name: ATP-dependent RNA helicase DDX3Y isoform 1
• NCBI Official Synonym Full Names: DEAD-box helicase 3 Y-linked
• NCBI Official Symbol: DDX3Y
• NCBI Official Synonym Symbols: DBY
• NCBI Protein Information: ATP-dependent RNA helicase DDX3Y
• UniProt Protein Name: ATP-dependent RNA helicase DDX3Y
• Protein Family: ATP-dependent RNA helicase
• UniProt Gene Name: DDX3Y
• UniProt Synonym Gene Names: DBY

NCBI Description

The protein encoded by this gene is a member of the DEAD-box RNA helicase family, characterized by nine conserved motifs, included the conserved Asp-Glu-Ala-Asp (DEAD) motif. These motifs are thought to be involved in ATP binding, hydrolysis, RNA binding, and in the formation of intramolecular interactions. This protein shares high similarity to DDX3X, on the X chromosome, but a deletion of this gene is not complemented by DDX3X. Mutations in this gene result in male infertility, a reduction in germ cell numbers, and can result in Sertoli-cell only sydrome. Pseudogenes sharing similarity to both this gene and the DDX3X paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]

Uniprot Description

Probable ATP-dependent RNA helicase. May play a role in spermatogenesis.