Testing Data
anti-Human, Mouse ACTHR Antibody | anti-ACTHR antibody
ACTHR Antibody
Gene Names
MC2R; ACTHR
Reactivity
Human, Mouse
Applications
Western Blot, Immunofluorescence, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
ACTHR; ACTHR Antibody; ACTH receptor; ACTH-R; adrenocorticotropic hormone receptor; adrenocorticotropin receptor; MC2-R; melanocortin-2 receptor; anti-ACTHR antibody
Reactivity
Human, Mouse
Specificity
ACTHR antibody detects endogenous levels of total ACTHR protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
297
Applicable Applications for anti-ACTHR antibody
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:20000
IF: 1:100~1:500
ELISA: 1:20000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human ACTHR.
Preparation and Storage
Store at-20 degree C for 1 year.
Testing Data
Testing Data
Western Blot (WB)
(Peptide-+ Western blot analysis of extracts from HeLa cells, using ACTHR antibody. Immunofluorescence analysis of MCF-7 cells, using ACTHR antibody.)
Western Blot (WB)
(Peptide-+ Western blot analysis of extracts from HeLa cells, using ACTHR antibody. Immunofluorescence analysis of MCF-7 cells, using ACTHR antibody.)
Product Categories/Family for anti-ACTHR antibody
References
Mountjoy K.G., Science 257:1248-1251(1992). Gantz I., J. Biol. Chem. 268:8246-8250(1993). Metherell L.A., Nat. Genet. 37:166-170(2005).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
33,927 Da
NCBI Official Full Name
adrenocorticotropic hormone receptor
NCBI Official Synonym Full Names
melanocortin 2 receptor
NCBI Official Symbol
MC2R
NCBI Official Synonym Symbols
ACTHR
NCBI Protein Information
adrenocorticotropic hormone receptor
UniProt Protein Name
Adrenocorticotropic hormone receptor
UniProt Gene Name
MC2R
UniProt Synonym Gene Names
ACTHR; ACTH receptor; ACTH-R; MC2-R
NCBI Description
MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. Alternate transcript variants have been found for this gene. [provided by RefSeq, May 2014]
Uniprot Description
Receptor for corticotropin (ACTH). This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase (cAMP).
Research Articles on ACTHR
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Product Notes
The ACTHR mc2r (Catalog #AAA855105) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The ACTHR Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ACTHR can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF), ELISA (EIA). WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:20000. Researchers should empirically determine the suitability of the ACTHR mc2r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ACTHR, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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