CD52 recombinant antibody
Anti-CD52 [YTH 34.5-G2b (Campath-1G)]
Gene Names
CD52; CDW52
Reactivity
Human, Rhesus Monkey
Applications
Cytotoxicity Assay, ELISA, Immunohistochemistry, Flow Cytometry, Functional Assay, Western Blot
Purity
Protein A Affinity Purified
Synonyms
CD52; Anti-CD52 [YTH 34.5-G2b (Campath-1G)]; CDw52; Cambridge pathology 1 antigen; Epididymal secretory protein E5; Human epididymis-specific protein 5; CD52 recombinant antibody
Reactivity
Human, Rhesus Monkey
Isotype
Mouse IgG1, kappa
Clone Number
YTH 34.5-G2b (Campath-1G)
Specificity
Human CD52 antigen, also known as CAMPATH-1. CD52 is expressed at high density by lymphocytes, monocytes, eosinophils, thymocytes and macrophages. It is expressed by most lymphoid derived malignancies, although expression on myeloma cells is variable.
Purity/Purification
Protein A Affinity Purified
Sequence Length
61
Applicable Applications for CD52 recombinant antibody
Cytotoxicity Assay, ELISA (EIA), Immunohistochemistry (IHC) Formalin/Paraffin, In Vivo, Flow Cytometry (FC/FACS), Western Blot (WB)
Buffer Composition
PBS only with 0.02% Proclin 300.
Immunogen
Human peripheral mononuclear cells enriched for T-cells.
Chimeric Use Statement
This is a chimeric mouse antibody, based on the original rat IgG2b format, created for improved compatibility with existing reagents, assays and techniques.
Preparation and Storage
Store at 4 degree C for up to 3 months. For longer storage, aliquot and store at -20 degree C.
Related Product Information for CD52 recombinant antibody
Recombinant monoclonal antibody to CD52. Manufactured using a Recombinant Platform with variable regions (i.e. specificity) from the hybridoma YTH 34.5-G2b (Campath-1G). This is a chimeric mouse antibody, based on the original rat IgG2b format, created for improved compatibility with existing reagents, assays and techniques.
Product Categories/Family for CD52 recombinant antibody
References
Hale G et al. Removal of T cells from bone marrow for transplantation: a monoclonal antilymphocyte antibody that fixes human complement. Blood. 1983 Oct; 62(4):873-82. PMID:6349718
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
6,614 Da
NCBI Official Full Name
CAMPATH-1 antigen
NCBI Official Synonym Full Names
CD52 molecule
NCBI Official Symbol
CD52
NCBI Official Synonym Symbols
CDW52
NCBI Protein Information
CAMPATH-1 antigen
UniProt Protein Name
CAMPATH-1 antigen
Protein Family
UniProt Gene Name
CD52
UniProt Synonym Gene Names
CDW52; HE5; He5
UniProt Entry Name
CD52_HUMAN
Uniprot Description
CD52: May play a role in carrying and orienting carbohydrate, as well as having a more specific role.
Protein type: Membrane protein, GPI anchor; Membrane protein, integral
Chromosomal Location of Human Ortholog: 1p36
Cellular Component: integral to plasma membrane; membrane
Biological Process: elevation of cytosolic calcium ion concentration
Research Articles on CD52
Similar Products
Product Notes
The CD52 cd52 (Catalog #AAA488133) is a Recombinant Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-CD52 [YTH 34.5-G2b (Campath-1G)] reacts with Human, Rhesus Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's CD52 can be used in a range of immunoassay formats including, but not limited to, Cytotoxicity Assay, ELISA (EIA), Immunohistochemistry (IHC) Formalin/Paraffin, In Vivo, Flow Cytometry (FC/FACS), Western Blot (WB). Researchers should empirically determine the suitability of the CD52 cd52 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD52, Recombinant Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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