Pepsinogen I Active Protein | PGA3 active protein
Pepsinogen I (PGI/PGA), Human Stomach
Purity
>= 90% (SDS-PAGE, may contain minor cleavage products)
Synonyms
Pepsinogen I; Pepsinogen I (PGI/PGA); Human Stomach; Pepsinogen A; PGA3 active protein
Host
Human Gastric Mucosa
Purity/Purification
>= 90% (SDS-PAGE, may contain minor cleavage products)
Form/Format
Powder, Lyophilized from tris chloride, pH 8.5
E.C. Number
3.4.23.1
Appearance
White to off-white powder
Unit Definition
One unit will produce a (DELTA) A280 of 0.001 per minute at pH 2.0 and 37°C, measured as TCA-soluble products from hemoglobin.
Solubility
Clear, Colorless (1mg/mL 0.002 M Tris-Chloride, pH=8.0 buffer)
Protein
0.1mg protein/vial (E0.1%280nm =1.48)
Specific Activity
1340 U/mg protein (after activation)
Handling
Handle as a potentially hazardous substance. After reconstitution maintain at or above pH 8.0 to avoid activation.
Preparation and Storage
Store at -20°C
Storage Note: Protect from moisture
Shipping Note: Blue Ice
Storage Note: Protect from moisture
Shipping Note: Blue Ice
Related Product Information for PGA3 active protein
MyBioSource is the leading producer and supplier of human gastric Pepsinogen I (A) antigen as a cancer marker for medical research, clinical and biomedical manufacturing.
Custom preparations, technical support, bulk quantities and aliquoting available.
Human Pepsinogens are aspartic proteases produced in the gastric mucosa and secreted into the gastric lumen that play a major role in the digestion of proteins after activation of acidic pH. It is synthesized as isoymogens and are classified into two groups, Pepsinogen I and Pepsinogen II).
Human PGA and PGC antigen have been investigated as a possible biomarker for early detection of, Gastric cancer (GC), adenoma (GA) and severe atrophic (diffuse or patchy) corpus gastritis.
It has been reported that human Pepsinogen I (PGA) levels were lower in atrophic corpus gastritis than in atrophic antral gastritis, and human pepsinogen I(PGA) levels were lower in advanced gastric cancer than early stage gastric cancer.
Custom preparations, technical support, bulk quantities and aliquoting available.
Human Pepsinogens are aspartic proteases produced in the gastric mucosa and secreted into the gastric lumen that play a major role in the digestion of proteins after activation of acidic pH. It is synthesized as isoymogens and are classified into two groups, Pepsinogen I and Pepsinogen II).
Human PGA and PGC antigen have been investigated as a possible biomarker for early detection of, Gastric cancer (GC), adenoma (GA) and severe atrophic (diffuse or patchy) corpus gastritis.
It has been reported that human Pepsinogen I (PGA) levels were lower in atrophic corpus gastritis than in atrophic antral gastritis, and human pepsinogen I(PGA) levels were lower in advanced gastric cancer than early stage gastric cancer.
Product Categories/Family for PGA3 active protein
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Product Notes
The PGA3 (Catalog #AAA173573) is an Active Protein produced from Human Gastric Mucosa and is intended for research purposes only. The product is available for immediate purchase. 0. Researchers should empirically determine the suitability of the PGA3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Pepsinogen I, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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