Human ZNF147 ELISA Kit | ZNF147 elisa kit
ZNF147 Colorimetric Cell-Based ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene. [provided by RefSeq, Jul 2008]
Uniprot Description
TRIM25: a ubiquitous protein that mediates estrogen action in various target organs. Contains one RING-type zinc finger and one SPRY domain.
Protein type: EC 6.3.2.19; EC 6.3.2.n3; Ligase; Nuclear receptor co-regulator; Transcription factor; Ubiquitin conjugating system; Ubiquitin ligase
Chromosomal Location of Human Ortholog: 17q22
Cellular Component: cytosol; nuclear body; nucleoplasm
Molecular Function: cadherin binding; DNA binding transcription factor activity; ligase activity; protein binding; RNA binding; ubiquitin protein ligase activity involved in ERAD pathway; ubiquitin-protein transferase activity; zinc ion binding
Biological Process: bypass DNA synthesis; defense response to virus; ER-associated protein catabolic process; ERAD pathway; innate immune response; negative regulation of type I interferon production; negative regulation of viral release from host cell; negative regulation of virion penetration into host cell; positive regulation of I-kappaB kinase/NF-kappaB signaling; positive regulation of NF-kappaB transcription factor activity; positive regulation of transcription factor activity; protein deubiquitination; protein monoubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; regulation of viral entry into host cell; regulation of viral release from host cell; response to estrogen; response to vitamin D; viral process
Research Articles on ZNF147
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Product Notes
The Human ZNF147 trim25 (Catalog #AAA9500840) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9500840 ELISA Kit recognizes Human ZNF147. It is sometimes possible for the material contained within the vial of "ZNF147, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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