Human Xaa-Pro aminopeptidase 1 (XPNPEP1) ELISA Kit | XPNPEP1 elisa kit
Human Xaa-Pro aminopeptidase 1 (XPNPEP1) ELISA Kit
Gene Names
XPNPEP1; APP1; SAMP; XPNPEP; XPNPEPL; XPNPEPL1
Reactivity
Human
Synonyms
Xaa-Pro aminopeptidase 1 (XPNPEP1); Human Xaa-Pro aminopeptidase 1 (XPNPEP1) ELISA Kit; RP11-451M19.1; SAMP; XPNPEP; XPNPEPL; XPNPEPL1; X-Pro aminopeptidase 1; soluble; X-prolyl aminopeptidase (aminopeptidase P)-like; Xaa-Pro aminopeptidase 1; aminoacylproline aminopeptidase; aminopeptidas; XPNPEP1 elisa kit
Reactivity
Human
Specificity
This assay has high sensitivity and excellent specificity for detection of Human XPNPEP1. No significant cross-reactivity or interference between Human XPNPEP1 and analogues was observed.
Sequence Length
642
Assay Type
Quantitive Sandwich
Samples
Serum, Plasma, Other Biological Fluids
Detection Wavelength
450 nm
Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%)
= SD/meanX100
Intra-Assay
CV
Inter-Assay
CV
Preparation and Storage
Store at 2-8 degree C.
Related Product Information for XPNPEP1 elisa kit
Description: This assay employs a two-site sandwich ELISA to quantitate XPNPEP1 in samples. An antibody specific for XPNPEP1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any XPNPEP1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for XPNPEP1 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of XPNPEP1 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Overview: X-prolyl aminopeptidase is a proline-specific metalloaminopeptidase that specifically catalyzes the removal of any unsubstituted N-terminal amino acid that is adjacent to a penultimate proline residue. Because of its specificity toward proline, it has been suggested that X-prolyl aminopeptidase is important in the maturation and degradation of peptide hormones, neuropeptides, and tachykinins, as well as in the digestion of otherwise resistant dietary protein fragments, thereby complementing the pancreatic peptidases.
XPNPEPL, that encodes a 623-amino acid protein exhibiting 44% sequence identity and 62% sequence similarity to pig kidney X-prolyl aminopeptidase and high sequence homology to proteins in S. pombe and S. cerevisiae.
Overview: X-prolyl aminopeptidase is a proline-specific metalloaminopeptidase that specifically catalyzes the removal of any unsubstituted N-terminal amino acid that is adjacent to a penultimate proline residue. Because of its specificity toward proline, it has been suggested that X-prolyl aminopeptidase is important in the maturation and degradation of peptide hormones, neuropeptides, and tachykinins, as well as in the digestion of otherwise resistant dietary protein fragments, thereby complementing the pancreatic peptidases.
XPNPEPL, that encodes a 623-amino acid protein exhibiting 44% sequence identity and 62% sequence similarity to pig kidney X-prolyl aminopeptidase and high sequence homology to proteins in S. pombe and S. cerevisiae.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
72,107 Da
NCBI Official Full Name
xaa-Pro aminopeptidase 1 isoform 2
NCBI Official Synonym Full Names
X-prolyl aminopeptidase 1
NCBI Official Symbol
XPNPEP1
NCBI Official Synonym Symbols
APP1; SAMP; XPNPEP; XPNPEPL; XPNPEPL1
NCBI Protein Information
xaa-Pro aminopeptidase 1
UniProt Protein Name
Xaa-Pro aminopeptidase 1
UniProt Gene Name
XPNPEP1
UniProt Synonym Gene Names
sAmp
NCBI Description
This gene encodes the cytosolic form of a metalloaminopeptidase that catalyzes the cleavage of the N-terminal amino acid adjacent to a proline residue. The gene product may play a role in degradation and maturation of tachykinins, neuropeptides, and peptide hormones. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009]
Uniprot Description
Contributes to the degradation of bradykinin. Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro.
Research Articles on XPNPEP1
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Product Notes
The Human XPNPEP1 xpnpep1 (Catalog #AAA286639) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA286639 ELISA Kit recognizes Human XPNPEP1. It is sometimes possible for the material contained within the vial of "Xaa-Pro aminopeptidase 1 (XPNPEP1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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