Human Wingless Type MMTV Integration Site Family, Member 5B (WNT5B) ELISA Kit | WNT5B elisa kit
Human Wingless Type MMTV Integration Site Family, Member 5B (WNT5B) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 94% and 80% amino acid identity to the mouse Wnt5b protein and the human WNT5A protein, respectively. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]
Uniprot Description
WNT5B: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Interacts with PORCN. Belongs to the Wnt family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 12p13.3
Cellular Component: proteinaceous extracellular matrix; extracellular space; cell surface; endoplasmic reticulum lumen; Golgi lumen; plasma membrane; extracellular region
Molecular Function: frizzled binding; receptor binding
Biological Process: neuron differentiation; fat cell differentiation; Wnt receptor signaling pathway; cell fate commitment; wound healing; positive regulation of fat cell differentiation; chondrocyte differentiation; positive regulation of cell migration
Research Articles on WNT5B
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Product Notes
The Human WNT5B wnt5b (Catalog #AAA9307840) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9307840 ELISA Kit recognizes Human WNT5B. It is sometimes possible for the material contained within the vial of "Wingless Type MMTV Integration Site Family, Member 5B (WNT5B), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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