Human VSNL1 ELISA Kit | VSNL1 elisa kit

Human VSNL1(Visinin Like Protein 1)ELISA Kit 

Cat. Num. AAA2515713

• Gene Names: VSNL1; HLP3; VILIP; HPCAL3; HUVISL1; VILIP-1
• Reactivity: Human
• Synonyms: VSNL1; Human VSNL1(Visinin Like Protein 1)ELISA Kit ; VSNL1 elisa kit

• Reactivity: Human
• Specificity: This kit recognizes natural and recombinantHumanVSNL1. No significant cross-reactivity or interference between HumanVSNL1 and analogues was observed.
• Sequence Length: 191

• Samples: Serum, Plasma, Biological Fluids
• Assay Type: Sandwich
• Detection Range: 0.313-20ng/mL
• Sensitivity: Min: 0.188ng/mL; Max: 20ng/mL
• Preparation and Storage: Store at 4 degree C.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for VSNL1 elisa kit

Intended Uses: This ELISA kit applies to the invitro quantitative determination of HumanVSNL1concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to VSNL1. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for VSNL1and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain VSNL1, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of VSNL1.You can calculate the concentration of VSNL1in the samples by comparing the OD of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 21361559
• NCBI GeneID: 7447
• NCBI Accession #: NP_003376.2
• NCBI GenBank Nucleotide #: NM_003385.4
• Molecular Weight: 22,142 Da
• NCBI Official Full Name: visinin-like protein 1
• NCBI Official Synonym Full Names: visinin-like 1
• NCBI Official Symbol: VSNL1
• NCBI Official Synonym Symbols: HLP3; VILIP; HPCAL3; HUVISL1; VILIP-1
• NCBI Protein Information: visinin-like protein 1; VLP-1; hippocalcin-like protein 3
• UniProt Protein Name: Visinin-like protein 1
• Protein Family: Visinin-like protein
• UniProt Gene Name: VSNL1
• UniProt Synonym Gene Names: VISL1; VILIP; VLP-1; HLP3
• UniProt Entry Name: VISL1_HUMAN

NCBI Description

This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]

Uniprot Description

VSNL1: Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner. Belongs to the recoverin family.

Chromosomal Location of Human Ortholog: 2p24.3

Molecular Function: calcium ion binding

Biological Process: calcium-mediated signaling