Human Vascular Endothelial Growth Factor D (VEGFD) ELISA Kit | VEGFD elisa kit
Human Vascular Endothelial Growth Factor D (VEGFD) Mini Samples ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Sep 2011]
Uniprot Description
VEGFB: Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis. Homodimer; disulfide-linked. Can also form heterodimer with VEGF. Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas. Belongs to the PDGF/VEGF growth factor family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell cycle regulation; Cytokine; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 11q13.1
Cellular Component: extracellular region
Molecular Function: growth factor activity; protein binding
Biological Process: platelet degranulation; response to hypoxia; vascular endothelial growth factor receptor signaling pathway
Research Articles on VEGFD
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Product Notes
The Human VEGFD vegfb (Catalog #AAA2087276) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2087276 ELISA Kit recognizes Human VEGFD. It is sometimes possible for the material contained within the vial of "Vascular Endothelial Growth Factor D (VEGFD), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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