Testing Data
(The TFact TTF1 DNA-Binding ELISA detects active TTF1 in HepG2 and MCF7 Nuclear Extract. The HepG2 and MCF7 cells were grown 3 days in DMEM with 10% FBS and harvested for nuclear extract. )
Human TTF1 ELISA Kit | TTF1 elisa kit
TTF1 TFact DNA-Binding ELISA Kit
Testing Data
(The TFact TTF1 DNA-Binding ELISA detects active TTF1 in HepG2 and MCF7 Nuclear Extract. The HepG2 and MCF7 cells were grown 3 days in DMEM with 10% FBS and harvested for nuclear extract. )
Testing Data
(The TFact TTF1 DNA-Binding ELISA detects active TTF1 in HepG2 and MCF7 Nuclear Extract. The HepG2 and MCF7 cells were grown 3 days in DMEM with 10% FBS and harvested for nuclear extract. )
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a transcription termination factor that is localized to the nucleolus and plays a critical role in ribosomal gene transcription. The encoded protein mediates the termination of RNA polymerase I transcription by binding to Sal box terminator elements downstream of pre-rRNA coding regions. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. This gene shares the symbol/alias 'TFF1' with another gene, NK2 homeobox 1, also known as thyroid transcription factor 1, which plays a role in the regulation of thyroid-specific gene expression. [provided by RefSeq, Apr 2011]
Uniprot Description
TTF1: Multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. Plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5 recovers DNA-binding activity.
Protein type: DNA-binding; Nucleolus
Chromosomal Location of Human Ortholog: 9q34.13
Cellular Component: cytosol; nucleolus; nucleoplasm; nucleus; plasma membrane
Molecular Function: chromatin binding; sequence-specific DNA binding
Biological Process: cell differentiation; cellular protein metabolic process; chromatin remodeling; DNA-templated transcription, termination; negative regulation of DNA replication; regulation of transcription from RNA polymerase II promoter; termination of RNA polymerase I transcription; transcription initiation from RNA polymerase I promoter
Research Articles on TTF1
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Product Notes
The Human TTF1 ttf1 (Catalog #AAA9502301) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9502301 ELISA Kit recognizes Human TTF1. It is sometimes possible for the material contained within the vial of "TTF1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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