Human Translocator Protein (TSPO) ELISA Kit | TSPO elisa kit

Human Translocator Protein (TSPO) ELISA Kit

Cat. Num. AAA451442

• Gene Names: TSPO; DBI; IBP; MBR; PBR; PBS; BPBS; BZRP; PKBS; PTBR; mDRC; pk18
• Reactivity: Human
• Synonyms: Translocator Protein (TSPO); Human Translocator Protein (TSPO) ELISA Kit; IBP; PKBS; PBR; pk18; mDRC; MBR; BZRP; DBI; PTBR; Mitochondrial benzodiazepine receptor; Peripheral-Type Benzodiazepine Receptor/Recognition Site; TSPO elisa kit

• Reactivity: Human
• Sequence Length: 169

• Samples: Tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 0.312-20ng/mL
• Sensitivity: 0.128ng/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 74275350
• NCBI GeneID: 706
• NCBI Accession #: NP_000705.2
• NCBI GenBank Nucleotide #: NM_000714.5
• UniProt Accession #: P30536; Q53Y59; Q6ICF9; Q96TF6
• Molecular Weight: 10,537 Da
• NCBI Official Full Name: translocator protein
• NCBI Official Synonym Full Names: translocator protein
• NCBI Official Symbol: TSPO
• NCBI Official Synonym Symbols: DBI; IBP; MBR; PBR; PBS; BPBS; BZRP; PKBS; PTBR; mDRC; pk18
• NCBI Protein Information: translocator protein
• UniProt Protein Name: Translocator protein
• Protein Family: Translocator protein
• UniProt Gene Name: TSPO
• UniProt Synonym Gene Names: BZRP; MBR; PBR

NCBI Description

Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein. [provided by RefSeq, Feb 2012]

Uniprot Description

Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (). Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism (PubMed:24814875), but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides (PubMed:1847678).