Human Synuclein Gamma (SNCg) ELISA Kit | SNCg elisa kit

Human Synuclein Gamma (SNCg) ELISA Kit

Cat. Num. AAA2702731

• Reactivity: Human
• Synonyms: Synuclein Gamma (SNCg); Human Synuclein Gamma (SNCg) ELISA Kit; SNC-G; gSYN; SR; BCSG1; PERSYN; PRSN; Breast Cancer Specific Protein 1; Persyn; Synoretin; SNCg elisa kit

• Reactivity: Human
• Specificity: This assay has high sensitivity and excellent specificity for detection of SNCg. No significant cross-reactivity or interference between SNCg and analogues was observed.
• Sequence Length: 127

• Samples: Human serum, plasma, tissue homogenates, cell lysates and other biological fluids
• Assay Type: Quantitative Sandwich
• Detection Range: 31.2-2,000pg/mL
• Sensitivity: <13.1pg/mL
• Intra-assay Precision: Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level SNCg were tested 20 times on one plate, respectively. Intra-Assay: CV<10%
• Inter-assay Precision: Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level SNCg were tested on 3 different plates, 8 replicates in each plate. CV(%) = SD/meanX100. Inter-Assay: CV<12%
• Preparation and Storage: The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition.; To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for SNCg elisa kit

Intended Uses: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of SNCg in human serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Principle of the Assay: The microplate provided in this kit has been pre-coated with an antibody specific to SNCg. Standards or samples are then added to the appropriate microplate wells with a biotin-conjugated antibody specific to SNCg. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain SNCg, biotin-conjugated antibody and enzymeconjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm +/- 10nm. The concentration of SNCg in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 15705905
• Molecular Weight: 13,331 Da
• NCBI Official Full Name: synuclein gamma
• UniProt Protein Name: Gamma-synuclein
• Protein Family: Gamma-synuclein
• UniProt Gene Name: SNCG
• UniProt Synonym Gene Names: BCSG1; PERSYN; PRSN; SR

Uniprot Description

Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway ().