Human Synapsin III (SYN3) ELISA Kit | SYN3 elisa kit

Human Synapsin III (SYN3) ELISA Kit

Cat. Num. AAA9313003

• Reactivity: Human
• Synonyms: Synapsin III (SYN3); Human Synapsin III (SYN3) ELISA Kit; SYN3 elisa kit

• Reactivity: Human

• Samples: Undiluted original Human serum, plasma or tissue homogenates samples
• Assay Type: Quantitative Sandwich
• Detection Range: 3.12ng/ml-100ng/ml
• Sensitivity: 1.0ng/ml
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for SYN3 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only! This kit is intended to be used for determine the level of SYN3 (hereafter termed "analyte") in undiluted original Human serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 219518036
• NCBI GeneID: 8224
• UniProt Accession #: O14994; B1B1F9
• Molecular Weight: 63,303 Da
• NCBI Official Full Name: Synapsin III
• NCBI Official Synonym Full Names: synapsin III
• NCBI Official Symbol: SYN3
• NCBI Protein Information: synapsin-3; cN28H9.2 (synapsin III)
• UniProt Protein Name: Synapsin-3
• Protein Family: Synapsin
• UniProt Gene Name: SYN3
• UniProt Entry Name: SYN3_HUMAN

NCBI Description

This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. The protein encoded by this gene shares the synapsin family domain model, with domains A, C, and E exhibiting the highest degree of conservation. The protein contains a unique domain J, located between domains C and E. Based on this gene's localization to 22q12.3, a possible schizophrenia susceptibility locus, and the established neurobiological roles of the synapsins, this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of this gene and is transcribed in the opposite direction. Alternative splicing of this gene results in multiple splice variants that encode different isoforms. [provided by RefSeq, Oct 2008]

Uniprot Description

SYN3: neuronal phosphoprotein that may be involved in the regulation of neurotransmitter release and synaptogenesis. Binds ATP with high affinity and ADP with a lower affinity. This is consistent with a catalytic role of the C-domain in which ADP would be dissociated by cellular ATP after bound ATP was hydrolyzed. May represent a candidate gene for schizophrenia. Alternative splicing results in six variants; however, only three isoforms have been fully described.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 22q12.3

Cellular Component: synaptic vesicle; synaptic vesicle membrane; cell junction

Molecular Function: catalytic activity; ATP binding

Biological Process: metabolic process; neurotransmitter secretion; regulation of synaptic transmission, GABAergic