Human Synapsin II (SYN2) ELISA Kit | SYN2 elisa kit

Human Synapsin II (SYN2) ELISA Kit

Cat. Num. AAA9312722

• Gene Names: SYN2; SYNII; SYNIIa; SYNIIb
• Reactivity: Human
• Synonyms: Synapsin II (SYN2); Human Synapsin II (SYN2) ELISA Kit; SYN2 elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: undiluted original Human body fluids, tissue homogenates, secretions or feces samples
• Assay Type: Quantitative Sandwich
• Detection Range: 0.25 ng/ml - 8 ng/mL
• Sensitivity: 0.1 ng/mL
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for SYN2 elisa kit

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of SYN2 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 19924103
• NCBI GeneID: 6854
• NCBI Accession #: NP_598328.1
• NCBI GenBank Nucleotide #: NM_133625.3
• UniProt Accession #: Q92777; A8MY98
• Molecular Weight: 62,847 Da
• NCBI Official Full Name: synapsin-2 isoform IIa
• NCBI Official Synonym Full Names: synapsin II
• NCBI Official Symbol: SYN2
• NCBI Official Synonym Symbols: SYNII; SYNIIa; SYNIIb
• NCBI Protein Information: synapsin-2
• UniProt Protein Name: Synapsin-2
• Protein Family: Synapsin
• UniProt Gene Name: SYN2
• UniProt Entry Name: SYN2_HUMAN

NCBI Description

This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. The TIMP4 gene is located within an intron of this gene and is transcribed in the opposite direction. Mutations in this gene may be associated with abnormal presynaptic function and schizophrenia. Alternative splicing of this gene results in two transcripts. [provided by RefSeq, Jul 2008]

Uniprot Description

SYN2: neuronal phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal and to the cytoskeleton. May function in the regulation of neurotransmitter release and synaptogenesis. Mutations in this gene may be associated with abnormal presynaptic function and schizophrenia. Alternative splicing results in two isoforms.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 3p25

Cellular Component: synaptic vesicle membrane; synapse; cell junction

Molecular Function: catalytic activity; ATP binding

Biological Process: synaptic transmission; metabolic process; neurotransmitter secretion

Disease: Schizophrenia