Human Solute Carrier Family 15 Member 1 (SLC15A1) ELISA Kit | SLC15A1 elisa kit
Human Solute Carrier Family 15 Member 1 (SLC15A1) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Background: SLC15A1 encodes an intestinal hydrogen peptide cotransporter that is a member of the solute carrier family 15. The encoded protein is localized to the brush border membrane of the intestinal epithelium and mediates the uptake of di- and tripeptides from the lumen into the enterocytes. This protein plays an important role in the uptake and digestion of dietary proteins. This protein also facilitates the absorption of numerous peptidomimetic drugs.Studies indicated that it transports dipeptides and tripeptides but not free amino acids or peptides with more than 3 amino acid residues and that its driving force for uphill transport requires proton binding and presence of an inside-negative membrane potential. A membrane protein, HTP1, which appeared to be associated with the oligopeptide transporter, had also been cloned
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an intestinal hydrogen peptide cotransporter that is a member of the solute carrier family 15. The encoded protein is localized to the brush border membrane of the intestinal epithelium and mediates the uptake of di- and tripeptides from the lumen into the enterocytes. This protein plays an important role in the uptake and digestion of dietary proteins. This protein also facilitates the absorption of numerous peptidomimetic drugs. [provided by RefSeq, Apr 2010]
Uniprot Description
SLC15A1: Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides. May constitute a major route for the absorption of protein digestion end-products. Belongs to the PTR2/POT transporter (TC 2.A.17) family.
Protein type: Transporter; Membrane protein, multi-pass; Transporter, SLC family; Membrane protein, integral
Chromosomal Location of Human Ortholog: 13q32.3
Cellular Component: membrane; integral to plasma membrane; plasma membrane
Molecular Function: proton-dependent oligopeptide secondary active transmembrane transporter activity; peptide:hydrogen symporter activity
Biological Process: proton transport; protein transport; transport; digestion; ion transport; transmembrane transport
Research Articles on SLC15A1
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Product Notes
The Human SLC15A1 slc15a1 (Catalog #AAA9714293) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9714293 ELISA Kit recognizes Human SLC15A1. It is sometimes possible for the material contained within the vial of "Solute Carrier Family 15 Member 1 (SLC15A1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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