Typical Testing Data/Standard Curve (for reference only)
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Human Soluble Receptor For Advanced Glycation End Products (sRAGE) ELISA Kit | sRAGE elisa kit
Human Soluble Receptor For Advanced Glycation End Products (sRAGE) ELISA Kit
Gene Names
AGER; RAGE; SCARJ1
Reactivity
Human
Synonyms
Soluble Receptor For Advanced Glycation End Products (sRAGE); Human Soluble Receptor For Advanced Glycation End Products (sRAGE) ELISA Kit; sRAGE elisa kit
Reactivity
Human
Sequence Length
347
Assay Type
Sandwich
Preparation and Storage
Store at 2-8 degree C.
Typical Testing Data/Standard Curve (for reference only)
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Typical Testing Data/Standard Curve (for reference only)
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Related Product Information for sRAGE elisa kit
Principle of the Assay: Human Soluble Receptor for Advanced Glycation End Products (sRAGE) ELISA Kit employs a two-site sandwich ELISA to quantitate sRAGE in samples. An antibody specific for sRAGE has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any sRAGE present is bound by the immobilized antibody. After removing any unbound substances, HRP-Conjugated Human sRAGE detection antibody is added to the wells. Following a wash to remove any unbound HRP reagent, a Chromogen solution is added to the wells and color develops in proportion to the amount of sRAGE bound in the initial step. The color development is stopped and the intensity of the color is measured.
Background/Introduction: sRAGE is a member of the immunoglobulin superfamily of cell surface molecules. sRAGE is a receptor for various molecules, including the amyloidogenic form of serum amyloid A, amyloid-beta protein, members of the S100/calgranulin superfamily and advanced glycation end products. sRAGE lies within the major histocompatibility complex (MHC) class III region on chromosome 6.
Background/Introduction: sRAGE is a member of the immunoglobulin superfamily of cell surface molecules. sRAGE is a receptor for various molecules, including the amyloidogenic form of serum amyloid A, amyloid-beta protein, members of the S100/calgranulin superfamily and advanced glycation end products. sRAGE lies within the major histocompatibility complex (MHC) class III region on chromosome 6.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
soluble form of receptor for advanced glycation endproducts
NCBI Official Synonym Full Names
advanced glycosylation end-product specific receptor
NCBI Official Symbol
AGER
NCBI Official Synonym Symbols
RAGE; SCARJ1
NCBI Protein Information
advanced glycosylation end product-specific receptor
NCBI Description
The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847). [provided by RefSeq, May 2011]
Research Articles on sRAGE
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Product Notes
The Human sRAGE (Catalog #AAA9716563) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9716563 ELISA Kit recognizes Human sRAGE. It is sometimes possible for the material contained within the vial of "Soluble Receptor For Advanced Glycation End Products (sRAGE), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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