Human Short Transient Receptor Potential Channel 1 (TRPC1) ELISA Kit | TRPC1 elisa kit
Human Short Transient Receptor Potential Channel 1 (TRPC1) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Uniprot Description
TRPC1: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion. Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Channel, calcium; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 3q23
Cellular Component: integral to plasma membrane; plasma membrane; receptor complex
Molecular Function: calcium channel activity; cation channel activity; protein binding; store-operated calcium channel activity
Biological Process: calcium ion transport; cytosolic calcium ion homeostasis; manganese ion transport; melanin biosynthetic process; positive regulation of release of sequestered calcium ion into cytosol; response to calcium ion
Research Articles on TRPC1
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Product Notes
The Human TRPC1 trpc1 (Catalog #AAA9394569) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9394569 ELISA Kit recognizes Human TRPC1. It is sometimes possible for the material contained within the vial of "Short Transient Receptor Potential Channel 1 (TRPC1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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