Typical Testing Data/Standard Curve (for reference only)
Human Serine/threonine-protein kinase ATR ELISA Kit | ATR elisa kit
Human Serine/threonine-protein kinase ATR ELISA Kit
Gene Names
atr.L; atr; XATR; frp1; mec1; sckl; sckl1
Reactivity
Human
Synonyms
Serine/threonine-protein kinase ATR; Human Serine/threonine-protein kinase ATR ELISA Kit; Ataxia telangiectasia and Rad3-related protein; FRAP-related protein 1; ATR; FRP1; 2.7.11.1; ATR elisa kit
Reactivity
Human
Sequence Length
2655
Assay Type
Sandwich
Detection Range
0.625-40 ng/mL
Sensitivity
0.326 ng/mL
Intra-Assay CV
<=6.3%
Inter-Assay CV
<=7.6%
Recovery
99%
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
301,459 Da
NCBI Official Full Name
serine/threonine-protein kinase atr
NCBI Official Synonym Full Names
ATR serine/threonine kinase L homeolog
NCBI Official Symbol
atr.L
NCBI Official Synonym Symbols
atr; XATR; frp1; mec1; sckl; sckl1
NCBI Protein Information
serine/threonine-protein kinase atr
UniProt Protein Name
Serine/threonine-protein kinase atr
Protein Family
UniProt Gene Name
atr
UniProt Synonym Gene Names
Xatr
UniProt Entry Name
ATR_XENLA
Uniprot Description
Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates BRCA1, CHEK1, MCM2, RAD17, RPA2, SMC1 and p53/TP53, which collectively inhibit DNA replication and mitosis and promote DNA repair, recombination and apoptosis. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at sites of DNA damage, thereby regulating DNA damage response mechanism.
Research Articles on ATR
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Product Notes
The Human ATR atr (Catalog #AAA2887957) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2887957 ELISA Kit recognizes Human ATR. It is sometimes possible for the material contained within the vial of "Serine/threonine-protein kinase ATR, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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