Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Semenogelin-1 (SEMG1) Standard Curve.)
Human Semenogelin-1 (SEMG1) ELISA Kit | SEMG1 elisa kit
Human Semenogelin-1 (SEMG1) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Semenogelin-1 (SEMG1) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Semenogelin-1 (SEMG1) Standard Curve.)
Background: Semenogelin I is the predominant protein in semen. The encoded secreted protein is involved in the formation of a gel matrix that encases ejaculated spermatozoa. The prostate-specific antigen (PSA) protease processes this protein into smaller peptides, with each possibly having a separate function. The proteolysis process breaks down the gel matrix and allows the spermatozoa to move more freely. Two transcript variants encoding different isoforms have been found for this gene.An open reading frame of 1,386 nucleotides encoded a signal peptide and a mature protein of 439 amino acid residues, in which residues 85 to 136 were identical with a previously characterized semenogelin fragment. An abundant seminal vesicular mRNA transcript of 1.8 kb codes for semenogelin.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is the predominant protein in semen. The encoded secreted protein is involved in the formation of a gel matrix that encases ejaculated spermatozoa. This preproprotein is proteolytically processed by the prostate-specific antigen (PSA) protease to generate multiple peptide products that exhibit distinct functions. One of these peptides, SgI-29, is an antimicrobial peptide with antibacterial activity. This proteolysis process also breaks down the gel matrix and allows the spermatozoa to move more freely. This gene and another similar semenogelin gene are present in a gene cluster on chromosome 20. [provided by RefSeq, Feb 2016]
Uniprot Description
SEMG1: Predominant protein in semen. It participates in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. Fragments of semenogelin and/or fragments of the related proteins may contribute to the activation of progressive sperm movements as the gel-forming proteins are fragmented by KLK3/PSA. Belongs to the semenogelin family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide; Cancer Testis Antigen (CTA)
Chromosomal Location of Human Ortholog: 20q12-q13.2
Cellular Component: extracellular space; extracellular region; nucleus; secretory granule
Molecular Function: protein binding; structural molecule activity
Biological Process: insemination
Research Articles on SEMG1
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Product Notes
The Human SEMG1 semg1 (Catalog #AAA9714375) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9714375 ELISA Kit recognizes Human SEMG1. It is sometimes possible for the material contained within the vial of "Semenogelin-1 (SEMG1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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