Human RLN3 ELISA Kit | RLN3 elisa kit

Human RLN3 (Relaxin-3) ELISA Kit

Cat. Num. AAA2516020

• Gene Names: RLN3; H3; RXN3; ZINS4; insl7
• Reactivity: Human
• Synonyms: RLN3; Human RLN3 (Relaxin-3) ELISA Kit; RLN3 elisa kit

• Reactivity: Human
• Specificity: This kit recognizes natural and recombinant Human RLN3. No significant cross-reactivity or interference between Human RLN3 and analogues was observed.
• Sequence Length: 166

• Samples: Serum, Plasma, Biological Fluids
• Assay Type: Sandwich
• Detection Range: 31.25-2000pg/mL
• Sensitivity: Min: 18.75pg/mL; Max: 2000pg/mL
• Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Human RLN3 concentrations in serum, plasma and other biological fluids.
• Preparation and Storage: Store at 4 degree C.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for RLN3 elisa kit

Principle of the assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to RLN3. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for RLN3 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain RLN3, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of RLN3. You can calculate the concentration of RLN3 in the samples by comparing the OD of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 37181470
• NCBI GeneID: 117579
• Molecular Weight: 15,451 Da
• NCBI Official Full Name: RLN3
• NCBI Official Synonym Full Names: relaxin 3
• NCBI Official Symbol: RLN3
• NCBI Official Synonym Symbols: H3; RXN3; ZINS4; insl7
• NCBI Protein Information: relaxin-3; insulin-like 7; insulin-like peptide 7; insulin-like peptide INSL7; prorelaxin H3
• UniProt Protein Name: Relaxin-3
• Protein Family: Relaxin
• UniProt Gene Name: RLN3
• UniProt Synonym Gene Names: INSL7; RXN3; ZINS4; Insulin-like peptide 7
• UniProt Entry Name: REL3_HUMAN

NCBI Description

Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. The protein encoded by this gene is a member of the relaxin family. The active form of the encoded protein consists of an A chain and a B chain but their cleavage sites are not definitely described yet. It may play a role in neuropeptide signaling processes. [provided by RefSeq, Jul 2008]

Uniprot Description

RLN3: May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 (GPCR135) and relaxin-3 receptor-2 (GPCR142). Belongs to the insulin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: extracellular region

Molecular Function: protein binding; G-protein-coupled receptor binding; hormone activity