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Human Phosphoribosylformylglycinamidine Synthase (PFAS) ELISA Kit | PFAS elisa kit

Human Phosphoribosylformylglycinamidine Synthase (PFAS) ELISA Kit

Gene Names
PFAS; PURL; FGAMS; FGARAT
Reactivity
Human
Synonyms
Phosphoribosylformylglycinamidine Synthase (PFAS); Human Phosphoribosylformylglycinamidine Synthase (PFAS) ELISA Kit; PFAS elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Specificity
No significant cross-reactivity or interference between this analyte and analogues is observed.
Samples
Porcine Body Fluids, Tissue Homogenates, Secretions Or Feces Samples
Assay Type
Quantitative Sandwich
Detection Range
3.12 ng/ml-100 ng/ml
Sensitivity
1.0 ng/ml.
Intra-assay Precision
Intra-assay CV (%) is less than 15%
Inter-assay Precision
Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
Preparation and Storage
Store all reagents at 2-8 degree C
Related Product Information for PFAS elisa kit
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of PF4 (hereafter termed "analyte") in undiluted original Porcine body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
144,734 Da
NCBI Official Full Name
PFAS protein
NCBI Official Synonym Full Names
phosphoribosylformylglycinamidine synthase
NCBI Official Symbol
PFAS
NCBI Official Synonym Symbols
PURL; FGAMS; FGARAT
NCBI Protein Information
phosphoribosylformylglycinamidine synthase; FGAM synthase; FGAR amidotransferase; formylglycinamide ribotide synthetase; formylglycinamide ribotide amidotransferase
UniProt Protein Name
Phosphoribosylformylglycinamidine synthase
UniProt Gene Name
PFAS
UniProt Synonym Gene Names
KIAA0361; FGAM synthase; FGAMS; FGARAT
UniProt Entry Name
PUR4_HUMAN

NCBI Description

Purines are necessary for many cellular processes, including DNA replication, transcription, and energy metabolism. Ten enzymatic steps are required to synthesize inosine monophosphate (IMP) in the de novo pathway of purine biosynthesis. The enzyme encoded by this gene catalyzes the fourth step of IMP biosynthesis. [provided by RefSeq, Jul 2008]

Uniprot Description

PFAS: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate

Protein type: Nucleotide Metabolism - purine; Ligase; EC 6.3.5.3

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: cytoplasm; cytosol

Molecular Function: metal ion binding; phosphoribosylformylglycinamidine synthase activity; ATP binding

Biological Process: response to drug; purine ribonucleoside monophosphate biosynthetic process; nucleobase, nucleoside and nucleotide metabolic process; ribonucleoside monophosphate biosynthetic process; glutamine metabolic process; purine nucleotide biosynthetic process; purine base metabolic process; 'de novo' IMP biosynthetic process

Research Articles on PFAS

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Product Notes

The Human PFAS pfas (Catalog #AAA9312464) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9312464 ELISA Kit recognizes Human PFAS. It is sometimes possible for the material contained within the vial of "Phosphoribosylformylglycinamidine Synthase (PFAS), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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