Human Phospholipase C epsilon ELISA Kit | PLCE1 elisa kit

Human Phospholipase C epsilon ELISA Kit

Cat. Num. AAA3802161

• Gene Names: PLCE1; PLCE; PPLC; NPHS3
• Reactivity: Human
• Synonyms: Phospholipase C epsilon; Human Phospholipase C epsilon ELISA Kit; PLCE1 elisa kit

• Reactivity: Human
• Sequence Length: 1994

• Samples: Serum, plasma, cell culture supernate and other biological fluids
• Assay Type: Sandwich
• Detection Range: 0.75ng/ml-12ng/ml
• Sensitivity: 0.1 ng/ml

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for PLCE1 elisa kit

Intended Use: The Stop Solution changes the color from blue to yellow and the intensity of the color is measured at 450 nm using a spectrophotometer. In order to measure the concentration ofPHOSPHOLIPASE Cepsilon in the sample, This PHOSPHOLIPASE Cepsilon ELISA Kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of Optical Density versusPHOSPHOLIPASE Cepsilon concentration. The concentration ofPHOSPHOLIPASE Cepsilon in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 11065786
• NCBI GeneID: 51196
• NCBI Official Full Name: phospholipase C epsilon, partial
• NCBI Official Synonym Full Names: phospholipase C epsilon 1
• NCBI Official Symbol: PLCE1
• NCBI Official Synonym Symbols: PLCE; PPLC; NPHS3
• NCBI Protein Information: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
• Protein Family: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase

NCBI Description

This gene encodes a phospholipase enzyme that catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate to generate two second messengers: inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). These second messengers subsequently regulate various processes affecting cell growth, differentiation, and gene expression. This enzyme is regulated by small monomeric GTPases of the Ras and Rho families and by heterotrimeric G proteins. In addition to its phospholipase C catalytic activity, this enzyme has an N-terminal domain with guanine nucleotide exchange (GEF) activity. Mutations in this gene cause early-onset nephrotic syndrome; characterized by proteinuria, edema, and diffuse mesangial sclerosis or focal and segmental glomerulosclerosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Sep 2009]