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Human Phosphoglycee kinase 1 (PGK1) ELISA Kit | PGK1 elisa kit

Human Phosphoglycee kinase 1 (PGK1) ELISA Kit

Gene Names
PGK1; PGKA; MIG10; HEL-S-68p
Reactivity
Human
Synonyms
Phosphoglycee kinase 1 (PGK1); Human Phosphoglycee kinase 1 (PGK1) ELISA Kit; PGK1 elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Sequence Length
417
Assay Type
Competitive ELISA
Samples
Serum, Plasma, Cell Culture Supernatants, Body Fluid and Tissue Homogenate
Detection Range
100-2500pg/mL
Sensitivity
1.0pg/mL

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
41,429 Da
NCBI Official Full Name
phosphoglycerate kinase 1
NCBI Official Synonym Full Names
phosphoglycerate kinase 1
NCBI Official Symbol
PGK1
NCBI Official Synonym Symbols
PGKA; MIG10; HEL-S-68p
NCBI Protein Information
phosphoglycerate kinase 1
UniProt Protein Name
Phosphoglycerate kinase 1
Protein Family
UniProt Gene Name
PGK1
UniProt Synonym Gene Names
PGKA; PRP 2

NCBI Description

The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome. [provided by RefSeq, Jan 2014]

Uniprot Description

In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein) (PubMed:2324090). May play a role in sperm motility (PubMed:26677959).

Research Articles on PGK1

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Product Notes

The Human PGK1 pgk1 (Catalog #AAA7254387) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7254387 ELISA Kit recognizes Human PGK1. It is sometimes possible for the material contained within the vial of "Phosphoglycee kinase 1 (PGK1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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