Human Oxoglutarate Dehydrogenase (OGDH) ELISA Kit | OGDH elisa kit

Human Oxoglutarate Dehydrogenase (OGDH) ELISA Kit

Cat. Num. AAA453610

• Gene Names: OGDH; E1k; OGDC; AKGDH
• Reactivity: Human
• Synonyms: Oxoglutarate Dehydrogenase (OGDH); Human Oxoglutarate Dehydrogenase (OGDH) ELISA Kit; AKGDH; E1k; OGDC; Alpha-Ketoglutarate Dehydrogenase; Lipoamide; 2-Oxoglutarate Dehydrogenase E1 Component; Mitochondrial; OGDH elisa kit

• Reactivity: Human
• Sequence Length: 427

• Samples: Tissue homogenates, cell lysates and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 1.56-100ng/mL
• Sensitivity: 0.59ng/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 51873038
• NCBI GeneID: 4967
• NCBI Accession #: NP_001003941.1
• NCBI GenBank Nucleotide #: NM_001003941.2
• UniProt Accession #: Q02218; Q96DD3; Q9UDX0; B4E2U9; D3DVL0; E9PBM1
• Molecular Weight: 48,180 Da
• NCBI Official Full Name: 2-oxoglutarate dehydrogenase, mitochondrial isoform 2
• NCBI Official Synonym Full Names: oxoglutarate dehydrogenase
• NCBI Official Symbol: OGDH
• NCBI Official Synonym Symbols: E1k; OGDC; AKGDH
• NCBI Protein Information: 2-oxoglutarate dehydrogenase, mitochondrial
• UniProt Protein Name: 2-oxoglutarate dehydrogenase, mitochondrial
• UniProt Gene Name: OGDH
• UniProt Synonym Gene Names: OGDC-E1

NCBI Description

This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Sep 2009]

Uniprot Description

The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO2. It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).