Human NOSTRIN (Nitric Oxide Synthase Traffic Inducer) ELISA Kit | NOSTRIN elisa kit
Human NOSTRIN (Nitric Oxide Synthase Traffic Inducer) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.[supplied by OMIM, Apr 2004]
Uniprot Description
NOSTRIN: Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 2q31.1
Cellular Component: cytoskeleton; plasma membrane; nucleus
Molecular Function: protein binding; DNA binding
Biological Process: endocytosis; regulation of nitric-oxide synthase activity; signal transduction; negative regulation of transcription, DNA-dependent; nitric oxide metabolic process
Research Articles on NOSTRIN
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Product Notes
The Human NOSTRIN nostrin (Catalog #AAA7608085) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7608085 ELISA Kit recognizes Human NOSTRIN. It is sometimes possible for the material contained within the vial of "NOSTRIN (Nitric Oxide Synthase Traffic Inducer), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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