Human Neutrophil Activating Protein 3 (NAP3) ELISA Kit | NAP3 elisa kit

Human Neutrophil Activating Protein 3 (NAP3) ELISA Kit

Cat. Num. AAA453643

• Gene Names: CXCL1; FSP; GRO1; GROa; MGSA; NAP-3; SCYB1; MGSA-a
• Reactivity: Human
• Synonyms: Neutrophil Activating Protein 3 (NAP3); Human Neutrophil Activating Protein 3 (NAP3) ELISA Kit; NAP3; NAP3 elisa kit

• Reactivity: Human
• Sequence Length: 107

• Samples: Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 15.625-1000pg/mL
• Sensitivity: 6.5pg/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 4504153
• NCBI GeneID: 2919
• NCBI Accession #: NP_001502.1
• NCBI GenBank Nucleotide #: NM_001511.3
• UniProt Accession #: P09341; Q9UCR7
• Molecular Weight: 11,301 Da
• NCBI Official Full Name: growth-regulated alpha protein
• NCBI Official Synonym Full Names: C-X-C motif chemokine ligand 1
• NCBI Official Symbol: CXCL1
• NCBI Official Synonym Symbols: FSP; GRO1; GROa; MGSA; NAP-3; SCYB1; MGSA-a
• NCBI Protein Information: growth-regulated alpha protein
• UniProt Protein Name: Growth-regulated alpha protein
• UniProt Gene Name: CXCL1
• UniProt Synonym Gene Names: GRO; GRO1; GROA; MGSA; SCYB1; MGSA; NAP-3

NCBI Description

This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014]

Uniprot Description

Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity.