Human Neuron Navigator 3 (NAV3) ELISA Kit | NAV3 elisa kit

Human Neuron Navigator 3 (NAV3) ELISA Kit

Cat. Num. AAA9311562

• Gene Names: NAV3; POMFIL1; unc53H3; STEERIN3
• Reactivity: Human
• Synonyms: Neuron Navigator 3 (NAV3); Human Neuron Navigator 3 (NAV3) ELISA Kit; NAV3 elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: Undiluted original Human serum, plasma or tissue homogenates samples
• Assay Type: Quantitative Sandwich
• Detection Range: 3.12ng/ml-100ng/ml
• Sensitivity: 1.0ng/ml
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for NAV3 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only! This kit is intended to be used for determine the level of NAV3 (hereafter termed "analyte") in undiluted original Human serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 120953251
• NCBI GeneID: 89795
• NCBI Accession #: NP_055718.4
• NCBI GenBank Nucleotide #: NM_014903.4
• UniProt Accession #: Q8IVL0; Q8NFW7; Q9Y2E7
• Molecular Weight: 255,648 Da
• NCBI Official Full Name: neuron navigator 3
• NCBI Official Synonym Full Names: neuron navigator 3
• NCBI Official Symbol: NAV3
• NCBI Official Synonym Symbols: POMFIL1; unc53H3; STEERIN3
• NCBI Protein Information: neuron navigator 3; steerin 3; steerin-3; unc-53 homolog 3; pore membrane and/or filament interacting like protein 1; pore membrane and/or filament-interacting-like protein 1
• UniProt Protein Name: Neuron navigator 3
• Protein Family: Neuron navigator
• UniProt Gene Name: NAV3
• UniProt Synonym Gene Names: KIAA0938; POMFIL1; STEERIN3; unc53H3
• UniProt Entry Name: NAV3_HUMAN

NCBI Description

This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. Multiple alternatively spliced transcript variants for this gene have been described but only one has had its full-length nature determined. [provided by RefSeq, Jul 2008]

Uniprot Description

NAV3: May regulate IL2 production by T-cells. May be involved in neuron regeneration. A chromosomal aberration disrupting NAV3 has been found in patients with Sezary syndrome. Translocation t(12;18)(q21;q21.2). Belongs to the Nav/unc-53 family. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 12q14.3

Cellular Component: nuclear outer membrane