IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded Human colon cancer using Bakantibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigenretrieval.)
Rabbit anti-Human Bak Monoclonal Antibody | anti-Bak antibody
Bak Rabbit mAb
Gene Names
BAK1; BAK; CDN1; BCL2L7; BAK-LIKE
Reactivity
Human
Applications
Immunoprecipitation, Immunohistochemistry, Western Blot
Purity
Affinity Purified
Synonyms
Bak, Antibody; Bak Rabbit mAb; BAK1; BAK; BCL2L7; CDN1; Bcl-2 homologous antagonist/killer; Apoptosis regulator BAK; Bcl-2-like protein 7; Bcl2-L-7; anti-Bak antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Clone Number
R03-6A8
Purity/Purification
Affinity Purified
Form/Format
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Applicable Applications for anti-Bak antibody
IP (Immunoprecipitation), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide of human Bak
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze/thaw cycles.
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded Human colon cancer using Bakantibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigenretrieval.)
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded Human colon cancer using Bakantibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigenretrieval.)
WB (Western Blot)
(Western blot analysis of Bak in K562, Hela lysates using Bak antibody.)
WB (Western Blot)
(Western blot analysis of Bak in K562, Hela lysates using Bak antibody.)
Related Product Information for anti-Bak antibody
Bak is a proapoptotic member of the Bcl-2 family. This protein is located on the outer membrane of mitochondria and is an essential component for transduction of apoptotic signals through the mitochondrial pathway. Upon apoptotic stimulation, an upstream stimulator like truncated BID (tBID) induces conformational changes in Bak to form oligomer channels in the mitochondrial membrane for cytochrome c release. The release of cytochrome c to the cytosol activates the caspase-9 pathway and eventually leads to cell death
Product Categories/Family for anti-Bak antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
23,409 Da
NCBI Official Full Name
bcl-2 homologous antagonist/killer
NCBI Official Synonym Full Names
BCL2-antagonist/killer 1
NCBI Official Symbol
BAK1
NCBI Official Synonym Symbols
BAK; CDN1; BCL2L7; BAK-LIKE
NCBI Protein Information
bcl-2 homologous antagonist/killer; bcl2-L-7; BCL2-like 7 protein; bcl-2-like protein 7; apoptosis regulator BAK; pro-apoptotic protein BAK
UniProt Protein Name
Bcl-2 homologous antagonist/killer
UniProt Gene Name
BAK1
UniProt Synonym Gene Names
BAK; BCL2L7; CDN1; Bcl2-L-7
UniProt Entry Name
BAK_HUMAN
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Product Notes
The Bak bak1 (Catalog #AAA269278) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Bak Rabbit mAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Bak can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the Bak bak1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Bak, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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