Human Misshapen-Like Kinase 1 (MINK1) ELISA Kit | MINK1 elisa kit
Human Misshapen-Like Kinase 1 (MINK1) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Background: MINK1 encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. [provided by RefSeq, Mar 2016]
Uniprot Description
MINK: a protein kinase of the STE20 family. Studies of the mouse ortholog indicate increased expression during postnatal mouse cerebral development. Activates JNK and the p38 pathways. Three splicing isoforms have been described.
Protein type: Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Protein kinase, STE; EC 2.7.11.1; STE group; STE20 family; MSN subfamily
Chromosomal Location of Human Ortholog: 17p13.2
Cellular Component: Golgi apparatus; postsynaptic membrane; axon; dendrite; cytoplasm; postsynaptic density; cell junction; cytosol
Molecular Function: protein serine/threonine kinase activity; protein binding; ATP binding; receptor signaling protein serine/threonine kinase activity; protein kinase activity
Biological Process: regulation of cell-matrix adhesion; multicellular organismal development; protein amino acid autophosphorylation; dendrite morphogenesis; positive regulation of JNK cascade; negative thymic T cell selection; regulation of cell migration; protein amino acid phosphorylation; microvillus biogenesis; synaptic transmission; regulation of cell-cell adhesion; regulation of catalytic activity; actin cytoskeleton reorganization; JNK cascade; response to stress
Research Articles on MINK1
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Product Notes
The Human MINK1 mink1 (Catalog #AAA9715276) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9715276 ELISA Kit recognizes Human MINK1. It is sometimes possible for the material contained within the vial of "Misshapen-Like Kinase 1 (MINK1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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