Human Melanocortin receptor 4 (MC4R) ELISA Kit | MC4R elisa kit
Human Melanocortin receptor 4 (MC4R) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a membrane-bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by G proteins. This is an intronless gene. Defects in this gene are a cause of autosomal dominant obesity. [provided by RefSeq, Jan 2010]
Uniprot Description
MC4R: receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. A G-protein coupled receptor that stimulates adenylate cyclase. Defects are a cause of autosomal dominant obesity
Protein type: Membrane protein, integral; GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 18q22
Cellular Component: plasma membrane; integral to membrane; nucleus
Molecular Function: neuropeptide binding; protein binding; melanocortin receptor activity; melanocyte stimulating hormone receptor activity; peptide hormone binding; ubiquitin protein ligase binding
Biological Process: G-protein signaling, coupled to cAMP nucleotide second messenger; diet induced thermogenesis; insulin secretion; positive regulation of cAMP biosynthetic process; energy reserve metabolic process; positive regulation of bone resorption; feeding behavior; response to insulin stimulus
Disease: Obesity
Research Articles on MC4R
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Product Notes
The Human MC4R mc4r (Catalog #AAA9337240) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9337240 ELISA Kit recognizes Human MC4R. It is sometimes possible for the material contained within the vial of "Melanocortin receptor 4 (MC4R), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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