Typical Testing Data/Standard Curve (for reference only)
Human Low Density Lipoprotein Receptor Related Protein 8 (LRP8) ELISA Kit | LRP8 elisa kit
Human Low Density Lipoprotein Receptor Related Protein 8 (LRP8) ELISA Kit
Gene Names
LRP8; LR8B
Reactivity
Human
Synonyms
Low Density Lipoprotein Receptor Related Protein 8 (LRP8); Human Low Density Lipoprotein Receptor Related Protein 8 (LRP8) ELISA Kit; LRP8 elisa kit
Reactivity
Human
Sequence Length
917
Samples
Serum, plasma, cell culture supernates, cell lysates, tissue homogenates
Assay Type
Quantitative Sandwich
Detection Range
10ng/L - 4000ng/L
Sensitivity
5.14ng/L
Intra-Assay
CV<8%
Inter-Assay
CV<10%
Preparation and Storage
Store at 2 to 8 degree C for 6 months.
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Related Product Information for LRP8 elisa kit
Intended Uses: This sandwich kit is for the accurate quantitative detection of human Low Density Lipoprotein Receptor Related Protein 8 (also known as LRP8) in serum, plasma, cell culture supernates, cell lysates, tissue homogenates.
Principles of the Assay: This kit is an Enzyme-Linked Immunosorbent Assay (ELISA). The plate has been pre-coated with human LRP8 antibody. LRP8 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated human LRP8 Antibody is added and binds to LRP8 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated LRP8 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of human LRP8. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Principles of the Assay: This kit is an Enzyme-Linked Immunosorbent Assay (ELISA). The plate has been pre-coated with human LRP8 antibody. LRP8 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated human LRP8 Antibody is added and binds to LRP8 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated LRP8 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of human LRP8. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
101,379 Da
NCBI Official Full Name
low-density lipoprotein receptor-related protein 8
NCBI Official Synonym Full Names
LDL receptor related protein 8
NCBI Official Symbol
LRP8
NCBI Official Synonym Symbols
LR8B
NCBI Protein Information
low-density lipoprotein receptor-related protein 8
UniProt Protein Name
Low-density lipoprotein receptor-related protein 8
Protein Family
UniProt Gene Name
LRP8
UniProt Synonym Gene Names
LR8B; LRP-8
Uniprot Description
Cell surface receptor for Reelin (RELN) and apolipoprotein E (apoE)-containing ligands. Also binds alpha2-macroglobulin. LRP8 participates in transmitting the extracellular Reelin signal to intracellular signaling processes, by binding to DAB1 on its cytoplasmic tail. Reelin acts via both the VLDL receptor (VLDLR) and LRP8 to regulate DAB1 tyrosine phosphorylation and microtubule function in neurons. LRP8 has higher affinity for Reelin than VLDLR. LRP8 is thus a key component of the Reelin pathway which governs neuronal layering of the forebrain during embryonic brain development. Not required for endocytic uptake of SEPP1 in the kidney which is mediated by LRP2 ().
Research Articles on LRP8
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Product Notes
The Human LRP8 lrp8 (Catalog #AAA163729) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA163729 ELISA Kit recognizes Human LRP8. It is sometimes possible for the material contained within the vial of "Low Density Lipoprotein Receptor Related Protein 8 (LRP8), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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