Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Lipocalin-1 (LCN1) Standard Curve.)
Human Lipocalin-1 (LCN1) ELISA Kit | LCN1 elisa kit
Human Lipocalin-1 (LCN1) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Lipocalin-1 (LCN1) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Lipocalin-1 (LCN1) Standard Curve.)
Background: Lipocalin-1 belongs to the lipocalin family. Lipocalins are a group of extracellular proteins that are able to bind lipophiles by enclosure within their structures to minimize solvent contact. This protein may bind hydrophobic ligands and inhibit cysteine proteinases. It may also play a role in taste reception. Based on the known 3-dimensional structure of 5 members of the lipocalin family, i.e., retinol binding protein, beta-lactoglobulin, bilin binding protein, mouse major urinary protein, and rat urinary alpha-2-globulin, the general architecture appears to be highly appropriate for binding a variety of hydrophobic ligands. On the basis of highly conserved amino acid sequences and of a size around 18 to 20 kD, about 20 proteins have been designated as lipocalins.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the lipocalin family of small secretory proteins. Lipocalins are extracellular transport proteins that bind to a variety of hydrophobic ligands. The encoded protein is the primary lipid binding protein in tears and is overproduced in response to multiple stimuli including infection and stress. The encoded protein may be a marker for chromosome aneuploidy as well as an autoantigen in Sjogren's syndrome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and two pseudogenes of this gene are also located on the long arm of chromosome 9. [provided by RefSeq, Nov 2011]
Uniprot Description
LCN1: Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket. Belongs to the calycin superfamily. Lipocalin family.
Protein type: Secreted; Inhibitor; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 9q34
Cellular Component: extracellular space; extracellular region
Molecular Function: cysteine protease inhibitor activity
Biological Process: long-chain fatty acid transport; retinal homeostasis; sensory perception of taste; response to stimulus; proteolysis; transmembrane transport
Research Articles on LCN1
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Product Notes
The Human LCN1 lcn1 (Catalog #AAA9715511) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9715511 ELISA Kit recognizes Human LCN1. It is sometimes possible for the material contained within the vial of "Lipocalin-1 (LCN1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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