Human KIAA1853 ELISA Kit | KIAA1853 elisa kit
Human Serine/arginine repetitive matrix protein 4, KIAA1853 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
SRRM4 promotes alternative splicing and inclusion of neural-specific exons in target mRNAs (Calarco et al., 2009 [PubMed 19737518]).[supplied by OMIM, Oct 2009]
Uniprot Description
SRRM4: Splicing factor specifically required for neural cell differentiation. Acts in conjuction with nPTB/PTBP2 by binding directly to its regulated target transcripts and promotes neural- specific exon inclusion in many genes that function in neural cell differentiation. Required to promote the inclusion of neural- specific exon 10 in nPTB/PTBP2, leading to increased expression of neural-specific nPTB/PTBP2. Also promotes the inclusion of exon 16 in DAAM1 in neuron extracts. Belongs to the nSR100 family.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 12q24.23
Cellular Component: nucleus
Molecular Function: mRNA binding
Biological Process: nervous system development; sensory perception of sound; regulation of RNA splicing; RNA splicing; mRNA processing; cell differentiation; regulation of alternative nuclear mRNA splicing, via spliceosome
Research Articles on KIAA1853
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Product Notes
The Human KIAA1853 srrm4 (Catalog #AAA9339423) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9339423 ELISA Kit recognizes Human KIAA1853. It is sometimes possible for the material contained within the vial of "KIAA1853, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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