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Typical Testing Data/Standard Curve (for reference only)

Human integrin beta2, ITG beta2/CD11+CD18 ELISA Kit | ITG beta2/CD11+CD18 elisa kit

Human integrin beta2, ITG beta2/CD11+CD18 ELISA Kit

Gene Names
ITGB2; CD18
Reactivity
Human
Synonyms
integrin beta2; ITG beta2/CD11+CD18; Human integrin beta2; ITG beta2/CD11+CD18 ELISA Kit; ITG beta2/CD11+CD18 elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Sequence Length
769
Samples
Serum, Plasma, Cell Culture Supernates, Cell Lysates, Tissue Homogenates
Assay Type
Quantitative Sandwich
Detection Range
0.5ng/ml-150ng/ml
Sensitivity
0.24ng/ml
Intra-assay Precision
Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision. Intra-Assay: CV<8%
Inter-assay Precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision. CV(%) = SD/mean x 100. Inter-Assay: CV<10%
Preparation and Storage
Store at 2 to 8 degree C for 6 months.

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)
Related Product Information for ITG beta2/CD11+CD18 elisa kit
Intended Uses: This sandwich kit is for the accurate quantitative detection of human Insulin-like Peptide INSL5 (also known as INSL5) in serum, plasma, cell culture supernates, cell lysates, tissue homogenates.

Principle of the Assay: This kit is an Enzyme-Linked Immunosorbent Assay (ELISA). The plate has been pre-coated with human INSL5 antibody. INSL5 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated human INSL5 Antibody is added and binds to INSL5 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated INSL5 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of human INSL5. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
84,790 Da
NCBI Official Full Name
integrin beta-2
NCBI Official Symbol
ITGB2
NCBI Official Synonym Symbols
CD18
NCBI Protein Information
integrin beta-2
UniProt Protein Name
Integrin beta-2
UniProt Gene Name
ITGB2
UniProt Synonym Gene Names
CD18

Uniprot Description

Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. Contributes to natural killer cell cytotoxicity. Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation. Integrin alpha-L/beta-2 in association with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages.

Research Articles on ITG beta2/CD11+CD18

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Product Notes

The Human ITG beta2/CD11+CD18 itgb2 (Catalog #AAA164030) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA164030 ELISA Kit recognizes Human ITG beta2/CD11+CD18. It is sometimes possible for the material contained within the vial of "integrin beta2, ITG beta2/CD11+CD18, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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