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Testing Data (The OmniKine Human IL-1 R1 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human IL-1 R1 proteins within the range of 125-8000 pg/ml.)

Human IL-1 R1 ELISA Kit | IL-1 R1 elisa kit

IL-1 R1 (Human) OmniKine ELISA Kit

Gene Names
IL1R1; P80; IL1R; IL1RA; CD121A; D2S1473; IL-1R-alpha
Reactivity
Human
Synonyms
IL-1 R1; IL-1 R1 (Human) OmniKine ELISA Kit; Interleukin-1 receptor type 1; CD121 antigen-like family member A; Interleukin-1 receptor alpha; p80; IL1R; IL1RA; IL1RT1; IL-1 R1 elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Specificity
The OmniKine Human IL-1 R1 ELISA is capable of recognizing both recombinant and naturally produced Human IL-1 R1 proteins. The antigens listed below were tested at 50 ng/ml and did not exhibit significant cross reactivity or interference.
Human: IL-1RA, IL-1R AcP, IL-1 Rrp2, IL-1 sR2
Murine: IL-1 R1
Form/Format
12 x 8-Well Microstrips
Sequence Length
569
Samples
Plasma, serum, lysate
Assay Type
Sandwich ELISA
Detection Range
125-8000 pg/ml
Sensitivity
125-8000 pg/ml
Detection Method
Colorimetric 450 nm
Subtype
None
Preparation and Storage
Store at 4 degree C for 6 months.

Testing Data

(The OmniKine Human IL-1 R1 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human IL-1 R1 proteins within the range of 125-8000 pg/ml.)

Testing Data (The OmniKine Human IL-1 R1 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human IL-1 R1 proteins within the range of 125-8000 pg/ml.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
65,402 Da
NCBI Official Full Name
interleukin-1 receptor type 1 isoform 1
NCBI Official Synonym Full Names
interleukin 1 receptor type 1
NCBI Official Symbol
IL1R1
NCBI Official Synonym Symbols
P80; IL1R; IL1RA; CD121A; D2S1473; IL-1R-alpha
NCBI Protein Information
interleukin-1 receptor type 1
UniProt Protein Name
Interleukin-1 receptor type 1
UniProt Gene Name
IL1R1
UniProt Synonym Gene Names
IL1R; IL1RA; IL1RT1; IL-1R-1; IL-1RT-1; IL-1RT1; IL-1R-alpha; mIL-1R1; mIL-1RI; sIL-1R1; sIL-1RI

NCBI Description

This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12. [provided by RefSeq, Dec 2013]

Uniprot Description

IL-1RA: Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. Belongs to the interleukin-1 receptor family.

Protein type: EC 2.7.11.25; Membrane protein, integral; Receptor, cytokine

Chromosomal Location of Human Ortholog: 2q11.2-q12.1

Cellular Component: external side of plasma membrane; extracellular region; integral component of plasma membrane; intracellular membrane-bound organelle; membrane; plasma membrane

Molecular Function: interleukin-1 binding; interleukin-1 receptor activity; interleukin-1, Type I, activating receptor activity; platelet-derived growth factor receptor binding; protease binding; protein binding; signal transducer activity; transmembrane receptor activity

Biological Process: cell surface receptor signaling pathway; immune response; positive regulation of interleukin-1-mediated signaling pathway; positive regulation of neutrophil extravasation; regulation of inflammatory response

Research Articles on IL-1 R1

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Product Notes

The Human IL-1 R1 il1r1 (Catalog #AAA9501954) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9501954 ELISA Kit recognizes Human IL-1 R1. It is sometimes possible for the material contained within the vial of "IL-1 R1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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