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Human ICAM-1 ELISA Kit | ICAM-1 elisa kit

ICAM-1 Colorimetric Cell-Based ELISA Kit

Gene Names
ICAM1; BB2; CD54; P3.58
Reactivity
Human
Synonyms
ICAM-1; ICAM-1 Colorimetric Cell-Based ELISA Kit; Intercellular adhesion molecule 1; Major group rhinovirus receptor; CD54; ICAM1; ICAM-1 elisa kit
Ordering
 
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For Research Use Only!
Reactivity
Human
Form/Format
One 96-Well Plate
Sequence Length
532
Samples
Researchers plate their cell line of choice
Assay Type
Non-Phospho Cell-Based ELISA
Sensitivity
>=5000 cells/well
Detection Method
Colorimetric 450 nm
Preparation and Storage
Store at 4 degree C.
Product Categories/Family for ICAM-1 elisa kit

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
57825
NCBI Official Full Name
intercellular adhesion molecule 1
NCBI Official Synonym Full Names
intercellular adhesion molecule 1
NCBI Official Symbol
ICAM1
NCBI Official Synonym Symbols
BB2; CD54; P3.58
NCBI Protein Information
intercellular adhesion molecule 1
UniProt Protein Name
Intercellular adhesion molecule 1
UniProt Gene Name
ICAM1
UniProt Synonym Gene Names
ICAM-1

NCBI Description

This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008]

Uniprot Description

ICAM1: a type I membrane protein of the immunoglobulin superfamily. Is a ligand for the leukocyte adhesion LFA-1 protein (Integrin alpha-L/beta-2) and a Rhinovirus receptor. Typically expressed on endothelial cells and cells of the immune system. ICAM1 binds to integrins of type CD11a / CD18, or CD11b / CD18. Its expression is activated by p53 in an NF-kappaB-independent manner. Induced by TNFalpha in a process that involves IKKbeta.

Protein type: Cell adhesion; Immunoglobulin superfamily; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: cell surface; external side of plasma membrane; extracellular exosome; extracellular matrix; extracellular space; focal adhesion; immunological synapse; integral component of plasma membrane; membrane; membrane raft; plasma membrane

Molecular Function: integrin binding; protein binding; receptor activity; transmembrane receptor activity; viral receptor activity

Biological Process: acute inflammatory response to antigenic stimulus; adhesion of symbiont to host; cell adhesion; cell adhesion mediated by integrin; cell aging; cellular response to alkaloid; cellular response to dexamethasone stimulus; cellular response to glucose stimulus; cellular response to hypoxia; cellular response to interleukin-1; cellular response to interleukin-6; cellular response to nutrient levels; cellular response to tumor necrosis factor; entry of virus into host cell; establishment of endothelial intestinal barrier; extracellular matrix organization; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; leukocyte adhesion; leukocyte migration; membrane to membrane docking; negative regulation of calcium ion transport; negative regulation of endothelial cell apoptotic process; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; ovarian follicle development; positive regulation of actin filament polymerization; positive regulation of cellular extravasation; positive regulation of ERK1 and ERK2 cascade; positive regulation of GTPase activity; positive regulation of leukocyte adhesion to vascular endothelial cell; positive regulation of NF-kappaB transcription factor activity; positive regulation of nitric oxide biosynthetic process; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of vasoconstriction; receptor-mediated virion attachment to host cell; regulation of cell shape; regulation of immune response; regulation of leukocyte mediated cytotoxicity; regulation of ruffle assembly; response to amino acid; response to amphetamine; response to copper ion; response to drug; response to ethanol; response to gonadotropin; response to insulin stimulus; response to ionizing radiation; response to sulfur dioxide; sensory perception of sound; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; T cell antigen processing and presentation

Disease: Malaria, Susceptibility To

Research Articles on ICAM-1

1. High levels of serum ICAM-1 was associated with the development of multiple organ failure . High levels of VCAM-1 was associated with both multiple organ failure and in-hospital mortality.

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Product Notes

The Human ICAM-1 icam1 (Catalog #AAA9500303) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9500303 ELISA Kit recognizes Human ICAM-1. It is sometimes possible for the material contained within the vial of "ICAM-1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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