Human GSPT1/Eukaryotic peptide chain release factor GTP-binding subunit ERF3A ELISA Kit | GSPT1 elisa kit
Human GSPT1/Eukaryotic peptide chain release factor GTP-binding subunit ERF3A ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
GSPT1 iso3: Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ERF1. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Belongs to the GTP-binding elongation factor family. ERF3 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell cycle regulation; Hydrolase; RNA-binding; Translation
Chromosomal Location of Human Ortholog: 16p13.1
Cellular Component: intracellular
Molecular Function: GTPase activity; protein binding; GTP binding; translation release factor activity
Biological Process: protein amino acid methylation; mRNA catabolic process, nonsense-mediated decay; translational termination; G1/S transition of mitotic cell cycle
Research Articles on GSPT1
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Product Notes
The Human GSPT1 gspt1 (Catalog #AAA2903813) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2903813 ELISA Kit recognizes Human GSPT1. It is sometimes possible for the material contained within the vial of "GSPT1/Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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