Typical Testing Data/Standard Curve (for reference only)
Human GCH1 ELISA Kit | GCH1 elisa kit
Human GCH1 ELISA Kit
Gene Names
GCH1; GCH; DYT5; DYT14; DYT5a; GTPCH1; HPABH4B; GTP-CH-1
Reactivity
Human
Synonyms
GCH1; Human GCH1 ELISA Kit; GCH1 elisa kit
Reactivity
Human
Sequence Length
250
Samples
Serum, plasma, cell culture supernate and other biological fluids
Assay Type
Sandwich
Detection Range
15 IU/mL-240 IU/mL
Sensitivity
1 IU/ml
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Related Product Information for GCH1 elisa kit
Intended Use: The Stop Solution changes the color from blue to yellow and the intensity of the color is measured at 450 nm using a spectrophotometer. In order to measure the concentration ofGCH1in the sample, This GCH1ELISA Kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of Optical Density versusGCH1concentration. The concentration ofGCH1in the samples is then determined by comparing the O.D. of the samples to the standard curve.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
GTP cyclohydrolase 1 isoform 1
NCBI Official Synonym Full Names
GTP cyclohydrolase 1
NCBI Official Symbol
GCH1
NCBI Official Synonym Symbols
GCH; DYT5; DYT14; DYT5a; GTPCH1; HPABH4B; GTP-CH-1
NCBI Protein Information
GTP cyclohydrolase 1
UniProt Protein Name
GTP cyclohydrolase 1
Protein Family
UniProt Gene Name
GCH1
UniProt Synonym Gene Names
DYT5; GCH
UniProt Entry Name
GCH1_HUMAN
NCBI Description
This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme. [provided by RefSeq, Jul 2008]
Research Articles on GCH1
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Product Notes
The Human GCH1 gch1 (Catalog #AAA3802042) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA3802042 ELISA Kit recognizes Human GCH1. It is sometimes possible for the material contained within the vial of "GCH1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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