Human Forkhead Box Protein M1 (FOXM1) ELISA Kit | FOXM1 elisa kit
Human Forkhead Box Protein M1 (FOXM1) ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
FOXM1: a transcriptional activator factor. Contains 1 fork-head domain. May play a role in the control of cell proliferation. Appears to be expressed only in adult organs containing proliferating/cycling cells or in response to growth factors. Also expressed in epithelial cell lines derived from tumors. Not expressed in resting cells. Phosphorylated in M (mitotic) phase. Three splice variant isoforms have been described. Isoform 1 and isoform 2 appear to be the only activators of gene transcription. Isoform 3, found in rat, does not seem to exist in human.
Protein type: DNA-binding; Transcription factor
Cellular Component: cytoplasm; nucleoplasm; nucleus
Molecular Function: DNA binding; protein binding; protein kinase binding; sequence-specific DNA binding; transcription factor activity
Biological Process: cell cycle; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; DNA repair; G2/M transition of mitotic cell cycle; liver development; negative regulation of stress-activated MAPK cascade; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of cell proliferation; regulation of Ras protein signal transduction; regulation of transcription, DNA-dependent; response to DNA damage stimulus; transcription from RNA polymerase II promoter; transcription, DNA-dependent; vasculogenesis
Research Articles on FOXM1
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Product Notes
The Human FOXM1 foxm1 (Catalog #AAA9350926) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9350926 ELISA Kit recognizes Human FOXM1. It is sometimes possible for the material contained within the vial of "Forkhead Box Protein M1 (FOXM1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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