Human FK506 binding protein 6, 36kDa (FKBP6) ELISA Kit | FKBP6 elisa kit

Human FK506 binding protein 6, 36kDa (FKBP6) ELISA Kit

Cat. Num. AAA2611033

• Gene Names: FKBP6; FKBP36
• Reactivity: Human
• Synonyms: FK506 binding protein 6; 36kDa (FKBP6); Human FK506 binding protein 6; 36kDa (FKBP6) ELISA Kit; FKBP6 elisa kit

• Reactivity: Human
• Specificity: No cross-reaction with other factors.
• Sequence Length: 327

• Samples: Human Serum, Plasma Or Cell Culture Supernatant And Organizations In The Natural And Recombinant Fibrin Concentration
• Assay Type: Sandwich
• Detection Range: 200 ng/ml-3.12 ng/ml
• Sensitivity: 0.6 ng/ml.
• Intra-assay Precision: <= 8%
• Inter-assay Precision: <= 12%
• Preparation and Storage: Store all reagents at 2-8 degree C.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for FKBP6 elisa kit

Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human Fibrin monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.

NCBI and Uniprot Product Information

• NCBI GI #: 22477287
• NCBI GeneID: 8468
• Molecular Weight: 36,874 Da
• NCBI Official Full Name: FK506 binding protein 6, 36kDa
• NCBI Official Synonym Full Names: FKBP prolyl isomerase 6
• NCBI Official Symbol: FKBP6
• NCBI Official Synonym Symbols: FKBP36
• NCBI Protein Information: inactive peptidyl-prolyl cis-trans isomerase FKBP6
• UniProt Protein Name: Inactive peptidyl-prolyl cis-trans isomerase FKBP6
• Protein Family: FK506-binding protein
• UniProt Gene Name: FKBP6
• UniProt Synonym Gene Names: FKBP36; Inactive PPIase FKBP6; 36 kDa FKBP; FKBP-36; FKBP-6

NCBI Description

The protein encoded by this gene is a cis-trans peptidyl-prolyl isomerase that may function in immunoregulation and basic cellular processes involving protein folding and trafficking. This gene is located in a chromosomal region that is deleted in Williams-Beuren syndrome. Defects in this gene may cause male infertility. There are multiple pseudogenes for this gene located nearby on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Uniprot Description

Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes ().