Human Fc Fragment Of IgG Low Affinity IIIb Receptor (FcgR3B) ELISA Kit | FcgR3B elisa kit

Human Fc Fragment Of IgG Low Affinity IIIb Receptor (FcgR3B) ELISA Kit

Cat. Num. AAA452241

• Gene Names: FCGR3B; CD16; FCG3; CD16b; FCGR3; FCR-10; FCRIII; FCRIIIb
• Reactivity: Human
• Synonyms: Fc Fragment Of IgG Low Affinity IIIb Receptor (FcgR3B); Human Fc Fragment Of IgG Low Affinity IIIb Receptor (FcgR3B) ELISA Kit; CD16B; FCG3; Fc-gamma RIII; Fc-gamma RIIIb; Fc-gamma RIII-beta; FCGR3; FcR-10; FcRIII; FcRIIIb; IGFR3; IgG Fc receptor III-1; Low affinity immunoglobulin gamma Fc region receptor; FcgR3B elisa kit

• Reactivity: Human
• Sequence Length: 233

• Samples: Serum, plasma, tissue homogenates, cell lysates and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 1.25-80ng/mL
• Sensitivity: 0.55ng/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

NCBI and Uniprot Product Information

• NCBI GI #: 132814489
• NCBI GeneID: 2215
• NCBI Accession #: NP_000561.3
• NCBI GenBank Nucleotide #: NM_000570.4
• UniProt Accession #: O75015
• Molecular Weight: 26,216 Da
• NCBI Official Full Name: low affinity immunoglobulin gamma Fc region receptor III-B isoform 2
• NCBI Official Synonym Full Names: Fc fragment of IgG receptor IIIb
• NCBI Official Symbol: FCGR3B
• NCBI Official Synonym Symbols: CD16; FCG3; CD16b; FCGR3; FCR-10; FCRIII; FCRIIIb
• NCBI Protein Information: low affinity immunoglobulin gamma Fc region receptor III-B
• UniProt Protein Name: Low affinity immunoglobulin gamma Fc region receptor III-B
• Protein Family: Low affinity immunoglobulin gamma Fc region receptor
• UniProt Gene Name: FCGR3B
• UniProt Synonym Gene Names: CD16B; FCG3; FCGR3; IGFR3; Fc-gamma RIII; Fc-gamma RIIIb; FcRIII; FcRIIIb

NCBI Description

The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1. [provided by RefSeq, Aug 2012]

Uniprot Description

Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.