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Human F box/WD repeat containing protein 2 (FBXW2) ELISA Kit | FBXW2 elisa kit

Human F box/WD repeat containing protein 2 (FBXW2) ELISA Kit

Gene Names
FBXW2; Md6; FBW2; Fwd2
Reactivity
Human
Synonyms
F box/WD repeat containing protein 2 (FBXW2); Human F box/WD repeat containing protein 2 (FBXW2) ELISA Kit; FBXW2 elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Samples
Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
Assay Type
Competitive
Detection Range
50-1000pg/mL
Sensitivity
1.0pg/mL
Preparation and Storage
Store all reagents at 2-8 degree C.
Product Categories/Family for FBXW2 elisa kit

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
44,466 Da
NCBI Official Full Name
F-box/WD repeat-containing protein 2
NCBI Official Synonym Full Names
F-box and WD repeat domain containing 2
NCBI Official Symbol
FBXW2
NCBI Official Synonym Symbols
Md6; FBW2; Fwd2
NCBI Protein Information
F-box/WD repeat-containing protein 2; F-box and WD-40 domain protein 2; F-box and WD-40 domain-containing protein 2
UniProt Protein Name
F-box/WD repeat-containing protein 2
UniProt Gene Name
FBXW2
UniProt Synonym Gene Names
FBW2; FWD2
UniProt Entry Name
FBXW2_HUMAN

NCBI Description

F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats. [provided by RefSeq, Jul 2008]

Uniprot Description

FBXW2: Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 9q34

Cellular Component: cytoplasm

Molecular Function: protein binding; ubiquitin-protein ligase activity

Biological Process: protein ubiquitination; protein modification process; proteolysis

Research Articles on FBXW2

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Product Notes

The Human FBXW2 fbxw2 (Catalog #AAA7250724) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7250724 ELISA Kit recognizes Human FBXW2. It is sometimes possible for the material contained within the vial of "F box/WD repeat containing protein 2 (FBXW2), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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