Human ECSIT homolog (Drosophila) ELISA Kit | ECSIT elisa kit

Human Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial, ECSIT ELISA Kit

Cat. Num. AAA9321617

• Gene Names: ECSIT; SITPEC
• Reactivity: Human
• Synonyms: ECSIT homolog (Drosophila); Human Evolutionarily conserved signaling intermediate in Toll pathway; mitochondrial; ECSIT ELISA Kit; mitochondrial (ECSIT) ELISA kit; SITPEC; evolutionarily conserved signaling intermediate in Toll pathway; likely ortholog of mouse signaling intermediate in Toll pathway evolutionarily conserved; signaling intermediate in Toll pathwa; ECSIT elisa kit

• Reactivity: Human

• Assay Type: Quantitative Sandwich
• Detection Range: 0.625ng/ml-20ng/ml
• Sensitivity: 0.1ng/ml
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for ECSIT elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used for determine the level of ECSIT (hereafter termed "analyte") in undiluted original Human serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 215599065
• NCBI GeneID: 51295
• NCBI Accession #: NP_001135936.1
• NCBI GenBank Nucleotide #: NM_001142464.2
• UniProt Accession #: Q9BQ95; Q96HQ7; Q9NYI1; E9PAN9; K7EMM0
• Molecular Weight: 33,938 Da
• NCBI Official Full Name: evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial isoform 2
• NCBI Official Synonym Full Names: ECSIT signalling integrator
• NCBI Official Symbol: ECSIT
• NCBI Official Synonym Symbols: SITPEC
• NCBI Protein Information: evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; ECSIT homolog; likely ortholog of mouse signaling intermediate in Toll pathway evolutionarily conserved
• UniProt Protein Name: Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial
• Protein Family: Evolutionarily conserved signaling intermediate
• UniProt Gene Name: ECSIT
• UniProt Entry Name: ECSIT_HUMAN

Uniprot Description

ECSIT: Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development. Required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase. Belongs to the ECSIT family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: nucleoplasm; transcription factor complex; mitochondrion; cytoplasm; nucleus

Molecular Function: oxidoreductase activity, acting on NADH or NADPH; signal transducer activity; protein binding; transcription factor activity

Biological Process: BMP signaling pathway; mesoderm formation; innate immune response; regulation of oxidoreductase activity