Human Cytochrome-C (Cyt-C) ELISA Kit | Cyt-C elisa kit

Human Cytochrome-C (Cyt-C) ELISA Kit

Cat. Num. AAA3801438

• Gene Names: CYC1; UQCR4; MC3DN6
• Reactivity: Human
• Synonyms: Cytochrome-C (Cyt-C); Human Cytochrome-C (Cyt-C) ELISA Kit; Cyt-C elisa kit

• Reactivity: Human
• Sequence Length: 325

• Samples: Serum, plasma, cell culture supernate and other biological fluids
• Assay Type: Sandwich
• Detection Range: 12.5 nmol/L-200 nmol/L
• Sensitivity: 1 nmol/L

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for Cyt-C elisa kit

Intended Use: The Stop Solution changes the color from blue to yellow and the intensity of the color is measured at 450 nm using a spectrophotometer. In order to measure the concentration ofCYT-Cin the sample, This CYT-CELISA Kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of Optical Density versusCYT-Cconcentration. The concentration ofCYT-Cin the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 21359867
• NCBI GeneID: 1537
• NCBI Accession #: NP_001907.2
• NCBI GenBank Nucleotide #: NP_001907.2
• UniProt Accession #: P08574
• NCBI Official Full Name: cytochrome c1, heme protein, mitochondrial
• NCBI Official Synonym Full Names: cytochrome c1
• NCBI Official Symbol: CYC1
• NCBI Official Synonym Symbols: UQCR4; MC3DN6
• NCBI Protein Information: cytochrome c1, heme protein, mitochondrial
• UniProt Protein Name: Cytochrome c1, heme protein, mitochondrial
• UniProt Gene Name: CYC1
• UniProt Synonym Gene Names: Cytochrome c-1
• UniProt Entry Name: CY1_HUMAN

NCBI Description

This gene encodes a subunit of the cytochrome bc1 complex, which plays an important role in the mitochondrial respiratory chain by transferring electrons from the Rieske iron-sulfur protein to cytochrome c. Mutations in this gene may cause mitochondrial complex III deficiency, nuclear type 6. [provided by RefSeq, Dec 2013]

Uniprot Description

CYC1: This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain. Belongs to the cytochrome c family.

Protein type: Mitochondrial; Energy Metabolism - oxidative phosphorylation; Membrane protein, integral; Oxidoreductase

Chromosomal Location of Human Ortholog: 8q24.3

Cellular Component: membrane; mitochondrion; mitochondrial inner membrane; integral to membrane; nucleus

Molecular Function: electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity; iron ion binding; heme binding

Biological Process: cellular metabolic process; response to glucagon stimulus

Disease: Mitochondrial Complex Iii Deficiency, Nuclear Type 6