Typical Testing Data/Standard Curve (for reference only)
Human CRN ELISA Kit | CRN elisa kit
Human CRN (Corin) ELISA Kit
Gene Names
CRNKL1; CLF; CRN; Clf1; HCRN; SYF3; MSTP021
Reactivity
Human
Synonyms
CRN; Human CRN (Corin) ELISA Kit; CRN elisa kit
Reactivity
Human
Specificity
This assay has high sensitivity and excellent specificity for detection of Human CRN. No significant cross-reactivity or interference between Human CRN and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Human CRN and all the analogues, therefore, cross reaction may still exist.
Sequence Length
687
Samples
Serum, Plasma, Biological Fluids
Assay Type
Sandwich
Detection Range
78.125-5000pg/mL
Sensitivity
Min: 46.875pg/mL; Max: 5000pg/mL
Preparation and Storage
Store at 4 degree C.
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Related Product Information for CRN elisa kit
Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of CRN in human serum, plasma and other biological fluids
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human CRN. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Human CRN and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human CRN, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Human CRN. You can calculate the concentration of Human CRN in the samples by comparing the OD of the samples to the standard curve.
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human CRN. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Human CRN and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human CRN, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Human CRN. You can calculate the concentration of Human CRN in the samples by comparing the OD of the samples to the standard curve.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
7,946 Da
NCBI Official Full Name
crooked neck-like protein 1 isoform d
NCBI Official Synonym Full Names
crooked neck pre-mRNA splicing factor 1
NCBI Official Symbol
CRNKL1
NCBI Official Synonym Symbols
CLF; CRN; Clf1; HCRN; SYF3; MSTP021
NCBI Protein Information
crooked neck-like protein 1; Crn, crooked neck-like 1; SYF3 pre-mRNA-splicing factor; crooked neck homolog; crooked neck pre-mRNA splicing factor-like 1
UniProt Protein Name
Crooked neck-like protein 1
Protein Family
UniProt Gene Name
CRNKL1
UniProt Synonym Gene Names
CRN; hCrn
UniProt Entry Name
CRNL1_HUMAN
NCBI Description
The crooked neck (crn) gene of Drosophila is essential for embryogenesis and is thought to be involved in cell cycle progression and pre-mRNA splicing. A protein encoded by this human locus has been found to localize to pre-mRNA splicing complexes in the nucleus and is necessary for pre-mRNA splicing. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2013]
Uniprot Description
CRNKL1: Involved in pre-mRNA splicing process. Belongs to the crooked-neck family. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Spliceosome; RNA splicing; RNA processing
Chromosomal Location of Human Ortholog: 20p11.2
Cellular Component: spliceosome; cytoplasm; nuclear speck
Molecular Function: protein binding; RNA binding
Biological Process: nuclear mRNA splicing, via spliceosome; spliceosome assembly
Research Articles on CRN
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Product Notes
The Human CRN crnkl1 (Catalog #AAA2506890) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2506890 ELISA Kit recognizes Human CRN. It is sometimes possible for the material contained within the vial of "CRN, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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